Pneumococcal diagnosis and serotypes in childhood community-acquired pneumonia

Elemraid, Mohamed A., Sails, Andrew D., Thomas, Matthew F., Rushton, Stephen P., Perry, John D., Eltringham, Gary J. A., Spencer, David A., Eastham, Katherine M., Hampton, Fiona, Gennery, Andrew R. and Clark, Julia E. (2013) Pneumococcal diagnosis and serotypes in childhood community-acquired pneumonia. Diagnostic Microbiology and Infectious Disease, 76 2: 129-132. doi:10.1016/j.diagmicrobio.2013.02.012


Author Elemraid, Mohamed A.
Sails, Andrew D.
Thomas, Matthew F.
Rushton, Stephen P.
Perry, John D.
Eltringham, Gary J. A.
Spencer, David A.
Eastham, Katherine M.
Hampton, Fiona
Gennery, Andrew R.
Clark, Julia E.
Title Pneumococcal diagnosis and serotypes in childhood community-acquired pneumonia
Journal name Diagnostic Microbiology and Infectious Disease   Check publisher's open access policy
ISSN 0732-8893
1879-0070
Publication date 2013-06-01
Year available 2013
Sub-type Article (original research)
DOI 10.1016/j.diagmicrobio.2013.02.012
Open Access Status DOI
Volume 76
Issue 2
Start page 129
End page 132
Total pages 4
Place of publication Philadelphia, PA, United States
Publisher Elsevier
Language eng
Formatted abstract
The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced routinely in the UK from September 2006 and replaced by PCV13 in 2010. In a prospective study from 2009 to 2011 of 160 children aged ≤16 years with radiologically confirmed pneumonia, likely pneumococcal infections were identified in 26%. Detection of pneumococci was improved with polymerase chain reaction compared to culture (21.6% versus 6% of children tested, P = 0.0004). Where serotyping was possible, all (n = 23) were non-PCV7 but PCV13 serotypes; 1 (43.5%), 3 (21.7%), 7A/F, and 19A (17.4% each).
Keyword Diagnosis
Paediatrics
Pneumococcal conjugate vaccine
Pneumonia
Serotype
Streptococcus pneumoniae
Urinary pneumococcal antigen
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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