Microenvironment and HIV-related lymphomagenesis

Pantanowitz, Liron, Carbone, Antonino and Dolcetti, Riccardo (2015) Microenvironment and HIV-related lymphomagenesis. Seminars in Cancer Biology, 34 52-57. doi:10.1016/j.semcancer.2015.06.002


Author Pantanowitz, Liron
Carbone, Antonino
Dolcetti, Riccardo
Title Microenvironment and HIV-related lymphomagenesis
Journal name Seminars in Cancer Biology   Check publisher's open access policy
ISSN 1096-3650
1044-579X
Publication date 2015-10-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.semcancer.2015.06.002
Open Access Status Not Open Access
Volume 34
Start page 52
End page 57
Total pages 6
Place of publication London, United Kingdom
Publisher Academic Press
Language eng
Abstract Patients with HIV infection are at increased risk of developing non-Hodgkin lymphoma and Hodgkin lymphoma. While the pathogenesis of these lymphomas is incompletely understood, evidence indicates that immune deregulation, genetic alterations and cytokine production play an important role in HIV lymphomagenesis. The lymphoma microenvironment in this heterogeneous group of lymphomas plays an equally critical role in their development, growth and progression. Important components of the microenvironment in HIV-related lymphomas include EBV and/or HHV-8 coinfection, reactive inflammatory cells, tumor microvasculature, and soluble factors. This paper provides a brief overview of HIV-related lymphomas and focuses on their lymphomagenesis and microenvironment.
Keyword AIDS
EBV
HHV8
HIV
Lymphoma
Microenvironment
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Non HERDC
UQ Diamantina Institute Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 9 times in Thomson Reuters Web of Science Article | Citations
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