Target therapy in elderly breast cancer patients

Carli, Paolo, Turchet, Elisa, Quitadamo, Daniela, Spada, Antonella, Miolo, Gianmaria, Lamaj, Elda, Spazzapan, Simon, Di Lauro, Vincenzo, Dolcetti, Riccardo, Veronesi, Andrea and Crivellari, Diana (2012) Target therapy in elderly breast cancer patients. Critical Reviews in Oncology/Hematology, 83 3: 422-431. doi:10.1016/j.critrevonc.2011.12.004


Author Carli, Paolo
Turchet, Elisa
Quitadamo, Daniela
Spada, Antonella
Miolo, Gianmaria
Lamaj, Elda
Spazzapan, Simon
Di Lauro, Vincenzo
Dolcetti, Riccardo
Veronesi, Andrea
Crivellari, Diana
Title Target therapy in elderly breast cancer patients
Journal name Critical Reviews in Oncology/Hematology   Check publisher's open access policy
ISSN 1040-8428
1879-0461
Publication date 2012-09-01
Year available 2012
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.critrevonc.2011.12.004
Open Access Status Not yet assessed
Volume 83
Issue 3
Start page 422
End page 431
Total pages 10
Place of publication E Park, Shannon, Clare Ireland
Publisher Elsevier Ireland
Language eng
Abstract Substantial progress has been made in the management of breast cancer by targeting HER2 and VEGF pathways. Although the efficacy and safety of target therapy in breast cancer have been established, no specific phase III trial has addressed these issues in the elderly population and the only data available derive from subanalyses or retrospective series. The aim of this review is to summarize the available evidence in this special population and to encourage further well designed studies in elderly breast cancer patients.
Keyword Bevacizumab
Breast cancer
Elderly
Lapatinib
Trastuzumab
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
 
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