The impact of Wolbachia on virus infection in mosquitoes

Johnson, Karyn N. (2015) The impact of Wolbachia on virus infection in mosquitoes. Viruses, 7 11: 5705-5717. doi:10.3390/v7112903


Author Johnson, Karyn N.
Title The impact of Wolbachia on virus infection in mosquitoes
Journal name Viruses   Check publisher's open access policy
ISSN 1999-4915
Publication date 2015-11-04
Year available 2015
Sub-type Critical review of research, literature review, critical commentary
DOI 10.3390/v7112903
Open Access Status DOI
Volume 7
Issue 11
Start page 5705
End page 5717
Total pages 13
Place of publication Basel, Switzerland
Publisher MDPI AG
Language eng
Abstract Mosquito-borne viruses such as dengue, West Nile and chikungunya viruses cause significant morbidity and mortality in human populations. Since current methods are not sufficient to control disease occurrence, novel methods to control transmission of arboviruses would be beneficial. Recent studies have shown that virus infection and transmission in insects can be impeded by co-infection with the bacterium Wolbachia pipientis. Wolbachia is a maternally inherited endosymbiont that is commonly found in insects, including a number of mosquito vector species. In Drosophila, Wolbachia mediates antiviral protection against a broad range of RNA viruses. This discovery pointed to a potential strategy to interfere with mosquito transmission of arboviruses by artificially infecting mosquitoes with Wolbachia. This review outlines research on the prevalence of Wolbachia in mosquito vector species and the impact of antiviral effects in both naturally and artificially Wolbachia-infected mosquitoes.
Keyword Wolbachia
Drosophila
Mosquito
Arbovirus
Insect virus
Symbiosis
Antiviral protection
Antiviral effects
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2016 Collection
School of Biological Sciences Publications
 
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