Residence time distributions of gas flowing through rotating drum bioreactors

Hardin, M. T., Howes, T. and Mitchell, D. A. (2001) Residence time distributions of gas flowing through rotating drum bioreactors. Biotechnology And Bioengineering, 74 2: 145-153. doi:10.1002/bit.1104

Author Hardin, M. T.
Howes, T.
Mitchell, D. A.
Title Residence time distributions of gas flowing through rotating drum bioreactors
Journal name Biotechnology And Bioengineering   Check publisher's open access policy
ISSN 0006-3592
Publication date 2001-01-01
Year available 2001
Sub-type Article (original research)
DOI 10.1002/bit.1104
Open Access Status Not yet assessed
Volume 74
Issue 2
Start page 145
End page 153
Total pages 9
Place of publication New York
Publisher John Wiley & Sons Inc
Language eng
Subject 270800 Biotechnology
Abstract Residence time distribution studies of gas through a rotating drum bioreactor for solid-state fermentation were performed using carbon monoxide as a tracer gas. The exit concentration as a function of time differed considerably from profiles expected for plug flow, plug flow with axial dispersion, and continuous stirred tank reactor (CSTR) models. The data were then fitted by least-squares analysis to mathematical models describing a central plug flow region surrounded by either one dead region (a three-parameter model) or two dead regions (a five-parameter model). Model parameters were the dispersion coefficient in the central plug flow region, the volumes of the dead regions, and the exchange rates between the different regions. The superficial velocity of the gas through the reactor has a large effect on parameter values. Increased superficial velocity tends to decrease dead region volumes, interregion transfer rates, and axial dispersion. The significant deviation from CSTR, plug flow, and plug flow with axial dispersion of the residence time distribution of gas within small-scale reactors can lead to underestimation of the calculation of mass and heat transfer coefficients and hence has implications for reactor design and scaleup. (C) 2001 John Wiley & Sons, Inc.
Keyword Biotechnology & Applied Microbiology
Residence Time Distribution (rtd)
Tracer Study
Mass Transfer
Rotating Drum Bioreactor
Mathematical Modeling
Solid-state Fermentation
Convective Mass-transfer
Transverse Bed Motion
Rotary Cylinders
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Chemical Engineering Publications
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Citation counts: TR Web of Science Citation Count  Cited 18 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 19 times in Scopus Article | Citations
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Created: Mon, 13 Aug 2007, 22:22:24 EST