Validation of the Chinese Western Ontario and McMaster Universities Osteoarthritis Index in patients from mainland China with osteoarthritis of the knee

Symonds, Tara, Hughes, Bernadette, Liao, Shanmei, Ang, Qiuqing and Bellamy, Nicholas (2015) Validation of the Chinese Western Ontario and McMaster Universities Osteoarthritis Index in patients from mainland China with osteoarthritis of the knee. Arthritis Care and Research, 67 11: 1553-1560. doi:10.1002/acr.22631


Author Symonds, Tara
Hughes, Bernadette
Liao, Shanmei
Ang, Qiuqing
Bellamy, Nicholas
Title Validation of the Chinese Western Ontario and McMaster Universities Osteoarthritis Index in patients from mainland China with osteoarthritis of the knee
Journal name Arthritis Care and Research   Check publisher's open access policy
ISSN 2151-4658
2151-464X
Publication date 2015-11-01
Year available 2015
Sub-type Article (original research)
DOI 10.1002/acr.22631
Open Access Status Not Open Access
Volume 67
Issue 11
Start page 1553
End page 1560
Total pages 8
Place of publication Hoboken NJ, United States
Publisher John Wiley & Sons
Language eng
Formatted abstract
Objective
To establish the reliability, validity, and sensitivity to change of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) among Chinese subjects with osteoarthritis (OA) of the knee, living in mainland China.

Methods
A multicenter, randomized, double-blind, placebo-controlled, parallel-group study was conducted for validation of the electronic personal digital assistant version of the WOMAC Numerical Rating Scale (NRS) 3.1 Index in China. A total of 287 subjects with OA of the knee were randomized to receive either meloxicam (15 mg) or placebo. Psychometric properties of the WOMAC were evaluated by estimating the reliability, validity, and sensitivity to change. Equivalence of the electronic version was also compared with the paper version.

Results
Intraclass correlation coefficients for the WOMAC pain, stiffness, and physical function subscales were 0.81, 0.76, and 0.85, respectively, indicating good test–retest reliability. Similarly, internal consistency was strong (Cronbach's alpha for the 3 WOMAC subscales was 0.84, 0.86, and 0.96, respectively). Pearson's correlation coefficients for WOMAC pain and Short Form 36 health survey (SF-36) bodily pain, as well as WOMAC physical function and SF-36 physical functioning domains were >0.4, indicating convergent validity, whereas the coefficients for all 3 WOMAC domains with SF-36 mental health and mental health component scores were <0.4, indicating divergent validity. There was strong discriminant validity between healthy volunteers and OA patients. The effect sizes of change from baseline to week 12 in WOMAC subscale scores were large, demonstrating sensitivity to change. Equivalence between paper and electronic versions was very high.

Conclusion
The culturally and linguistically validated Chinese version of the WOMAC NRS 3.1 for mainland China is psychometrically robust in its validity, reliability, and sensitivity to change for patients with OA of the knee.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 7 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 6 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 10 Nov 2015, 12:46:16 EST by System User on behalf of School of Medicine