Predictors of anxiety in multiple sclerosis

Hartoonian, Narineh, Terrill, Alexandra L., Beier, Meghan L., Turner, Aaron P., Day, Melissa A. and Alschuler, Kevin N. (2015) Predictors of anxiety in multiple sclerosis. Rehabilitation Psychology, 60 1: 91-98. doi:10.1037/rep0000019

Author Hartoonian, Narineh
Terrill, Alexandra L.
Beier, Meghan L.
Turner, Aaron P.
Day, Melissa A.
Alschuler, Kevin N.
Title Predictors of anxiety in multiple sclerosis
Journal name Rehabilitation Psychology   Check publisher's open access policy
ISSN 1939-1544
Publication date 2015-02-01
Year available 2015
Sub-type Article (original research)
DOI 10.1037/rep0000019
Open Access Status Not yet assessed
Volume 60
Issue 1
Start page 91
End page 98
Total pages 8
Place of publication Washington, DC, United States
Publisher American Psychological Association
Language eng
Formatted abstract
Purpose/Objectives: The aims of this study were to (1) identify the predictors of symptoms of anxiety, and (2) evaluate the differential association of somatic and nonsomatic symptoms of depression on anxiety over time in persons with multiple sclerosis (MS). Method/Design: Participants were 513 persons with MS who previously enrolled in a study exploring the experience of living with MS and completed a 4-month follow-up survey. The main outcome measure used was the Hospital Anxiety and Depression Scale–Anxiety. Demographic, disease-associated variables (time since onset of MS, Expanded Disability Status Scale Mobility, pain, and fatigue), and Time 1 psychological variables were entered into a hierarchical regression model to examine predictors at baseline for anxiety symptoms at Time 2. Results: A large portion of the sample was White (92%), female (82%), and had relapsing-remitting MS (57%). After adjusting for demographic and disease related variables, anxiety (β <.001), employment (β = .07), and nonsomatic depressive symptoms (β = .10) at baseline significantly predicted anxiety at Time 2, ps < .05. Interactions revealed significant effects for time since onset of MS and somatic symptoms as well as time since onset and nonsomatic symptoms, ps < .05. Nonsomatic symptoms were more linked to anxiety early in the disease and somatic symptoms were more prominently linked to anxiety later in the disease. Conclusions: Findings suggest that nonsomatic symptoms of depression and employment predict anxiety in MS. The relationship between different aspects of depression and anxiety may change over the course of the disease.
Keyword Multiple sclerosis
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
School of Psychology Publications
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Citation counts: TR Web of Science Citation Count  Cited 5 times in Thomson Reuters Web of Science Article | Citations
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Created: Fri, 30 Oct 2015, 03:56:40 EST by Melissa Day on behalf of Scholarly Communication and Digitisation Service