Oximes as reversible links in polymer chemistry: dynamic macromolecular stars

Mukherjee, Soma, Bapat, Abhijeet P., Hill, Megan R. and Sumerlin, Brent S. (2014) Oximes as reversible links in polymer chemistry: dynamic macromolecular stars. Polymer Chemistry, 5 24: 6923-6931. doi:10.1039/c4py01282h

Author Mukherjee, Soma
Bapat, Abhijeet P.
Hill, Megan R.
Sumerlin, Brent S.
Title Oximes as reversible links in polymer chemistry: dynamic macromolecular stars
Journal name Polymer Chemistry   Check publisher's open access policy
ISSN 1759-9962
Publication date 2014-12-21
Sub-type Article (original research)
DOI 10.1039/c4py01282h
Open Access Status Not Open Access
Volume 5
Issue 24
Start page 6923
End page 6931
Total pages 9
Place of publication Cambridge, United Kingdom
Publisher Royal Society of Chemistry
Language eng
Formatted abstract
We demonstrate the formation of oxime-functional macromolecular stars that are able to dissociate and reconstruct themselves upon application of a stimulus. The reversible nature of the oxime bond in the presence of externally added alkoxyamines or carbonyl compounds enables reconfiguration via competitive exchange. Reversible addition–fragmentation chain transfer (RAFT) polymerization was utilized to prepare well-defined amphiphilic block copolymers in which a hydrophobic keto-functional block allowed self-assembly into micelles in water. Adding a difunctional alkoxyamine small molecule to these solutions resulted in crosslinking of the micelles to yield macromolecular stars. The reversible nature of the O-alkyl oxime linkages was demonstrated via competitive exchange with excess of carbonyl compounds or monofunctional alkoxyamine under acidic conditions and at elevated temperatures to result in dissociation of the stars to unimolecular oxime-functional polymer chains.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 28 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 29 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Mon, 28 Sep 2015, 00:06:33 EST by Abhijeet Bapat on behalf of Examinations