The MEME Suite

Bailey, Timothy L., Johnson, James, Grant, Charles E. and Noble, William S. (2015) The MEME Suite. Nucleic Acids Research, 43 W1: W39-W49. doi:10.1093/nar/gkv416


Author Bailey, Timothy L.
Johnson, James
Grant, Charles E.
Noble, William S.
Title The MEME Suite
Journal name Nucleic Acids Research   Check publisher's open access policy
ISSN 0305-1048
1362-4954
Publication date 2015-07-01
Year available 2015
Sub-type Article (original research)
DOI 10.1093/nar/gkv416
Open Access Status DOI
Volume 43
Issue W1
Start page W39
End page W49
Total pages 11
Place of publication Oxford, United Kingdom
Publisher Oxford University Press
Language eng
Subject 1311 Genetics
Abstract The MEME Suite is a powerful, integrated set of webbased tools for studying sequencemotifs in proteins, DNA and RNA. Such motifs encode many biological functions, and their detection and characterization is important in the study of molecular interactions in the cell, including the regulation of gene expression. Since the previous description of the MEME Suite in the 2009 Nucleic Acids Research Web Server Issue, we have added six new tools. Here we describe the capabilities of all the tools within the suite, give advice on their best use and provide several case studies to illustrate how to combine the results of various MEME Suite tools for successful motif-based analyses. The MEME Suite is freely available for academic use at http://meme-suite.org, and source code is also available for download and local installation.
Formatted abstract
The MEME Suite is a powerful, integrated set of web-based tools for studying sequence motifs in proteins, DNA and RNA. Such motifs encode many biological functions, and their detection and characterization is important in the study of molecular interactions in the cell, including the regulation of gene expression. Since the previous description of the MEME Suite in the 2009 Nucleic Acids Research Web Server Issue, we have added six new tools. Here we describe the capabilities of all the tools within the suite, give advice on their best use and provide several case studies to illustrate how to combine the results of various MEME Suite tools for successful motif-based analyses. The MEME Suite is freely available for academic use at http://meme-suite.org, and source code is also available for download and local installation.
Keyword Novo Motif Discovery
Chip Seq Data
Nucleotide Sequences
Targeting Signal
Dna
Binding
Tools
Evolution
Proteins
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID R01 GM103544
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
Institute for Molecular Bioscience - Publications
 
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