Basal ganglia and cortical networks for sequential ordering and rhythm of complex movements

Bednark, Jeffery G., Campbell, Megan E. J. and Cunnington, Ross (2015) Basal ganglia and cortical networks for sequential ordering and rhythm of complex movements. Frontiers in Human Neuroscience, 9 JULY: 1-13. doi:10.3389/fnhum.2015.00421

Author Bednark, Jeffery G.
Campbell, Megan E. J.
Cunnington, Ross
Title Basal ganglia and cortical networks for sequential ordering and rhythm of complex movements
Journal name Frontiers in Human Neuroscience   Check publisher's open access policy
ISSN 1662-5161
Publication date 2015-07-27
Sub-type Article (original research)
DOI 10.3389/fnhum.2015.00421
Open Access Status DOI
Volume 9
Issue JULY
Start page 1
End page 13
Total pages 13
Place of publication Lausanne, Switzerland
Publisher Frontiers Research Foundation
Language eng
Abstract Voluntary actions require the concurrent engagement and coordinated control of complex temporal (e.g., rhythm) and ordinal motor processes. Using high-resolution functional magnetic resonance imaging (fMRI) and multi-voxel pattern analysis (MVPA), we sought to determine the degree to which these complex motor processes are dissociable in basal ganglia and cortical networks. We employed three different finger-tapping tasks that differed in the demand on the sequential temporal rhythm or sequential ordering of submovements. Our results demonstrate that sequential rhythm and sequential order tasks were partially dissociable based on activation differences. The sequential rhythm task activated a widespread network centered around the supplementary motor area (SMA) and basal-ganglia regions including the dorsomedial putamen and caudate nucleus, while the sequential order task preferentially activated a fronto-parietal network. There was also extensive overlap between sequential rhythm and sequential order tasks, with both tasks commonly activating bilateral premotor, supplementary motor, and superior/inferior parietal cortical regions, as well as regions of the caudate/putamen of the basal ganglia and the ventro-lateral thalamus. Importantly, within the cortical regions that were active for both complex movements, MVPA could accurately classify different patterns of activation for the sequential rhythm and sequential order tasks. In the basal ganglia, however, overlapping activation for the sequential rhythm and sequential order tasks, which was found in classic motor circuits of the putamen and ventro-lateral thalamus, could not be accurately differentiated by MVPA. Overall, our results highlight the convergent architecture of the motor system, where complex motor information that is spatially distributed in the cortex converges into a more compact representation in the basal ganglia.
Keyword Basal ganglia
High-resolution fMRI
Motor control
Motor order
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
Official 2016 Collection
School of Psychology Publications
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Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
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