Diabetes in pregnancy outcomes: a systematic review and proposed codification of definitions

Feig, Denice S., Corcoy, Rosa, Jensen, Dorte M., Kautzky-Willer, Alexandra, Nolan, Christopher J., Oats, Jeremy J. N., Sacks, David A., Caimari, Francisca and Mcintyre, H. David (2015) Diabetes in pregnancy outcomes: a systematic review and proposed codification of definitions. Diabetes/Metabolism Research and Reviews, 31 7: 680-690. doi:10.1002/dmrr.2640

Author Feig, Denice S.
Corcoy, Rosa
Jensen, Dorte M.
Kautzky-Willer, Alexandra
Nolan, Christopher J.
Oats, Jeremy J. N.
Sacks, David A.
Caimari, Francisca
Mcintyre, H. David
Title Diabetes in pregnancy outcomes: a systematic review and proposed codification of definitions
Journal name Diabetes/Metabolism Research and Reviews   Check publisher's open access policy
ISSN 1520-7560
Publication date 2015-05-07
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1002/dmrr.2640
Open Access Status Not yet assessed
Volume 31
Issue 7
Start page 680
End page 690
Total pages 11
Place of publication Chichester, West Sussex, United Kingdom
Publisher John Wiley & Sons
Language eng
Subject 2724 Internal Medicine
2712 Endocrinology, Diabetes and Metabolism
1310 Endocrinology
Abstract Rising rates of diabetes in pregnancy have led to an escalation in research in this area. As in any area of clinical research, definitions of outcomes vary from study to study, making it difficult to compare research findings and draw conclusions. Our aim was to compile and create a repository of definitions, which could then be used universally. A systematic review of the literature was performed on published and ongoing randomized controlled trials in the area of diabetes in pregnancy between 01 Jan 2000 and 01 Jun 2012. Other sources included the World Health Organization and Academic Society Statements. The advice of experts was sought when appropriate definitions were lacking. Among the published randomized controlled trials on diabetes and pregnancy, 171 abstracts were retrieved, 64 full texts were reviewed and 53 were included. Among the ongoing randomized controlled trials published in ClinicalTrials.gov, 90 protocols were retrieved and 25 were finally included. The definitions from these were assembled and the final maternal definitions and foetal definitions were agreed upon by consensus. It is our hope that the definitions we have provided (i) will be widely used in the reporting of future studies in the area of diabetes in pregnancy, that they will (ii) facilitate future systematic reviews and formal meta analyses and (iii) ultimately improve outcomes for mothers and babies.
Keyword Diabetes mellitus
Gestational diabetes
Pregnancy in diabetic patients
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Early view of article. Published online 7 May, 2015.

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Mater Research Institute-UQ (MRI-UQ)
Official 2016 Collection
School of Medicine Publications
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