Natural Killer cell control of BRAFV600E mutant melanoma during targeted therapy

de Andrade, Lucas Ferrari, Ngiow, Shin Foong, Martinet, Ludovic and Smyth, Mark J. (2015) Natural Killer cell control of BRAFV600E mutant melanoma during targeted therapy. Oncoimmunology, 4 4: 1-3. doi:10.1080/2162402X.2014.998119


Author de Andrade, Lucas Ferrari
Ngiow, Shin Foong
Martinet, Ludovic
Smyth, Mark J.
Title Natural Killer cell control of BRAFV600E mutant melanoma during targeted therapy
Formatted title
Natural Killer cell control of BRAFV600E mutant melanoma during targeted therapy
Journal name Oncoimmunology   Check publisher's open access policy
ISSN 2162-402X
2162-4011
Publication date 2015-01-01
Sub-type Editorial
DOI 10.1080/2162402X.2014.998119
Open Access Status Not Open Access
Volume 4
Issue 4
Start page 1
End page 3
Total pages 3
Place of publication New York, United States
Publisher Taylor & Francis
Language eng
Formatted abstract
Pharmacologic inhibition of the mutant BRAFV600E protein in advanced BRAFV600E melanoma results in a high proportion of patients that respond, but few with durable responses. We have recently revealed that Natural Killer (NK) cells play an essential role in the BRAFV600E inhibitor control of melanoma metastases in mice that may be therapeutically exploited to help overcome drug resistance.
Keyword Braf
Cancer immunotherapy
Metastases
NK cells
Resistance
Antimelanoma activity
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Editorial
Collections: Non HERDC
School of Medicine Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 4 times in Scopus Article | Citations
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