Lessons from the Amsterdam Growth and Health Longitudinal Study

Ferreira, Isabel and van de Laar, Roel J. (2015). Lessons from the Amsterdam Growth and Health Longitudinal Study. In Peter Nilsson, Michael Olsen and Stephane Laurent (Ed.), Early Vascular Ageing (EVA): new directions in cardiovascular protection (pp. 33-44) Amsterdam, The Netherlands: Elsevier Academic Press. doi:10.1016/B978-0-12-801387-8.00005-3

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Author Ferreira, Isabel
van de Laar, Roel J.
Title of chapter Lessons from the Amsterdam Growth and Health Longitudinal Study
Title of book Early Vascular Ageing (EVA): new directions in cardiovascular protection
Place of Publication Amsterdam, The Netherlands
Publisher Elsevier Academic Press
Publication Year 2015
Sub-type Research book chapter (original research)
DOI 10.1016/B978-0-12-801387-8.00005-3
Year available 2015
ISBN 9780128013878
Editor Peter Nilsson
Michael Olsen
Stephane Laurent
Chapter number 5
Start page 33
End page 44
Total pages 12
Total chapters 31
Language eng
Formatted Abstract/Summary
The Amsterdam Growth and Health Longitudinal Study is one of a handful of long-term cohort studies that began in childhood/adolescence. The unique characteristics of this cohort, with many repeated measures on a wide range of lifestyle and biological cardiovascular risk factors covering periods from adolescence through adulthood, when arterial aging phenotypes were thoroughly characterized, has provided valuable information for the better understanding of the etiology of arterial aging. This chapter describes the cohort profile and summarizes its key findings on the early and lifelong determinants of carotid stiffness (used as a marker of early vascular aging). Emphasis was put on findings derived from a life course approach to the analyses of the repeated risk factor exposure data since adolescence. We were able to identify pivotal risk factors and pinpoint the critical periods earlier in life when these were likely to start exerting its deleterious effects on vascular aging later in life. Adoption of healthy lifestyle early in life and sustained throughout the life course are of utmost importance to prevent early vascular aging.
Keyword Arterial stiffness
Longitudinal studies
Early determinants of health
Q-Index Code B1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Book Chapter
Collections: Official 2016 Collection
School of Public Health Publications
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Created: Fri, 29 May 2015, 22:48:57 EST by Isabel Ferreira on behalf of School of Public Health