Determinants of weight loss success utilizing a meal replacement plan and/or exercise, in overweight and obese adults with asthma

Scott, Hayley A., Gibson, Peter G., Garg, Manohar L., Pretto, Jeffrey J., Morgan, Philip J., Callister, Robin and Wood, Lisa G. (2015) Determinants of weight loss success utilizing a meal replacement plan and/or exercise, in overweight and obese adults with asthma. Respirology, 20 2: 243-250. doi:10.1111/resp.12423


Author Scott, Hayley A.
Gibson, Peter G.
Garg, Manohar L.
Pretto, Jeffrey J.
Morgan, Philip J.
Callister, Robin
Wood, Lisa G.
Title Determinants of weight loss success utilizing a meal replacement plan and/or exercise, in overweight and obese adults with asthma
Journal name Respirology   Check publisher's open access policy
ISSN 1440-1843
1323-7799
Publication date 2015-02-01
Sub-type Article (original research)
DOI 10.1111/resp.12423
Open Access Status Not yet assessed
Volume 20
Issue 2
Start page 243
End page 250
Total pages 8
Place of publication Richmond, VIC Australia
Publisher Wiley-Blackwell Publishing Asia
Language eng
Formatted abstract
Background and objective

While weight loss has been shown to reduce obesity-related comorbidity, many weight loss treatments fail. Factors that enhance weight loss success are unknown, particularly in those with asthma. The aim of the study was to identify patient characteristics that predict weight loss success in adults with asthma.

Methods

Baseline and change in asthma characteristics and eating behaviours were investigated for relationships with weight loss and fat loss using multiple linear regression, in 38 overweight and obese adults with asthma randomized to dietary, exercise or combined interventions targeting weight loss for 10 weeks.

Results

Mean ± standard deviation weight loss was 6.6 ± 5.1 kg. Greater %weight loss and %fat loss was achieved in those with poorer asthma-related quality of life at baseline ((rs = 0.398, P = 0.015) and (rs = 0.455, P = 0.005) respectively), with 1.7% greater absolute weight loss at week 10 corresponding to each one unit reduction in the asthma-related quality of life score at baseline. Furthermore, a lower baseline forced expiratory volume in 1 s/forced vital capacity correlated with greater weight loss (rs = 0.398, P = 0.015). Male sex was associated with a 3.6 kg greater weight loss (P = 0.087). Reducing emotional eating during the programme was associated with greater weight loss in women (rs = 0.576, P = 0.010).

Conclusions

This study demonstrates that individuals with more severe asthma at baseline are more successful in achieving weight loss, which could be a consequence of greater motivation and could be used as a motivational tool within the clinical setting. Gender tailoring of weight loss programmes may be useful to enhance weight loss success. Future studies are urgently needed to establish predictors of long-term weight loss maintenance in those with asthma.
Keyword Asthma
Eating behaviour
Lung function
Obesity
Weight loss
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
School of Medicine Publications
 
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Created: Thu, 28 May 2015, 21:57:38 EST by Hayley Scott on behalf of School of Medicine