Monooxygenases play only a minor role in resistance to synthetic pyrethroids in the cattle tick, Boophilus microplus

Crampton, A. L., Green, P., Baxter, G. D. and Barker, S. C. (1999) Monooxygenases play only a minor role in resistance to synthetic pyrethroids in the cattle tick, Boophilus microplus. Experimental and Applied Acarology, 23 11: 897-905. doi:10.1023/A:1006245800759


Author Crampton, A. L.
Green, P.
Baxter, G. D.
Barker, S. C.
Title Monooxygenases play only a minor role in resistance to synthetic pyrethroids in the cattle tick, Boophilus microplus
Journal name Experimental and Applied Acarology   Check publisher's open access policy
ISSN 0168-8162
1572-9702
Publication date 1999-01-01
Sub-type Article (original research)
DOI 10.1023/A:1006245800759
Open Access Status Not yet assessed
Volume 23
Issue 11
Start page 897
End page 905
Total pages 9
Place of publication Netherlands
Publisher Springer
Language eng
Subject C1
270300 Microbiology
630103 Beef cattle
Abstract We investigated the role of monooxygenases in resistance to synthetic pyrethroids (SPs) in the cattle tick, Boophilus microplus. We found that monooxygenases play only a minor role in resistance to SPs in both resistant and susceptible strains of B. microplus. We blocked the monooxygenases with piperonyl butoxide (PBO) and simultaneously applied the SPs, flumethrin and cypermethrin to larval B. microplus. PBO increased the effect of flumethrin (synergism ratios 2.7-8.9) more than it increased the effect of cypermethrin (synergism ratios 1.9-3.1). Of the four strains tested, Parkhurst, which is resistant to SPs, was the least affected by the addition of PBO (synergism ratios after cypermethrin was applied 1.9; after flumethrin 2.7) whereas N.R.F.S., the strain susceptible to SPs, was the most affected by synergism between PBO and SPs (synergism ratio after cypermethrin was applied 3.1; after flumethrin 8.9). We hypothesize that B. microplus lacks monooxygenases capable of conferring resistance to SPs because it and its recent ancestors were blood-feeders rather than herbivores.
Keyword Entomology
Boophilus Microplus
Tick
Ixodida
Resistance
Synthetic Pyrethroid
Monooxygenases
Ovis Schrank Phthiraptera
House-fly
Biochemical-characterization
Insecticide Resistance
Permethrin Resistance
Strains
Metabolism
Larvae
Trichodectidae
Blattellidae
Q-Index Code C1
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Institute for Molecular Bioscience - Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 8 times in Thomson Reuters Web of Science Article | Citations
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Created: Mon, 13 Aug 2007, 21:28:28 EST