Novel adaptations in motor cortical maps: the relation to persistent elbow pain

Schabrun, Siobhan M., Hodges, Paul W., Vicenzino, Bill, Jones, Emma and Chipchase, Lucinda S. (2015) Novel adaptations in motor cortical maps: the relation to persistent elbow pain. Medicine and Science in Sports and Exercise, 47 4: 681-690. doi:10.1249/MSS.0000000000000469


Author Schabrun, Siobhan M.
Hodges, Paul W.
Vicenzino, Bill
Jones, Emma
Chipchase, Lucinda S.
Title Novel adaptations in motor cortical maps: the relation to persistent elbow pain
Journal name Medicine and Science in Sports and Exercise   Check publisher's open access policy
ISSN 1530-0315
0195-9131
Publication date 2015-04-25
Year available 2015
Sub-type Article (original research)
DOI 10.1249/MSS.0000000000000469
Volume 47
Issue 4
Start page 681
End page 690
Total pages 10
Place of publication Philadelphia, PA United States
Publisher Lippincott Williams & Wilkins
Language eng
Formatted abstract
Introduction: Unilateral elbow pain results in sensorimotor dysfunction that is frequently bilateral, affects local and remote upper limb muscles, and persists beyond resolution of local tendon symptoms. These characteristics suggest supraspinal involvement. Here, we investigated 1) the excitability and organization of the M1 representation of the wrist extensor muscles and 2) the relation between M1 changes and clinical outcomes in lateral epicondylalgia (LE) (n = 11) and healthy control subjects (n = 11).

Methods: Transcranial magnetic stimulation was used to map the M1 representation of the extensor carpi radialis brevis (ECRB) and extensor digitorum (ED).

Results: The cortical representations of ECRB and ED were more excitable, and the centers of gravity for the two muscles were located closer together in LE than that in healthy controls. Increased ECRB excitability and closer location of the center of gravity were associated with higher pain severity at rest and/or in the preceding 6 months. A novel finding was a reduced number of discrete peaks in the representations of ECRB and ED in participants with LE compared with that in healthy controls.

Conclusions: This finding may have broad implications for the control of the wrist extensor muscles in LE. These data provide evidence that cortical organization may be maladaptive in LE and suggest that reorganization may be associated with persistence/recurrence of pain.
Keyword Elbow pain
Lateral epicondylalgia
Motor cortex organization
Transcranial magnetic stimulation
Wrist extensor muscles
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Health and Rehabilitation Sciences Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 14 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 18 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Sun, 17 May 2015, 11:16:27 EST by System User on behalf of School of Health & Rehabilitation Sciences