Nonleaching antimicrobial cotton fibers for hyaluronic acid adsorption

Wibowo, David and Lee, Cheng-Kang (2010) Nonleaching antimicrobial cotton fibers for hyaluronic acid adsorption. Biochemical Engineering Journal, 53 1: 44-51. doi:10.1016/j.bej.2010.09.002

Author Wibowo, David
Lee, Cheng-Kang
Title Nonleaching antimicrobial cotton fibers for hyaluronic acid adsorption
Journal name Biochemical Engineering Journal   Check publisher's open access policy
ISSN 1369-703X
Publication date 2010-12-15
Sub-type Article (original research)
DOI 10.1016/j.bej.2010.09.002
Volume 53
Issue 1
Start page 44
End page 51
Total pages 8
Place of publication Amsterdam, The Netherlands
Publisher Elsevier BV
Language eng
Formatted abstract
Quaternary ammonium containing compounds (QACs) such as cetylpyridinium chloride (CPC) is commonly employed in hyaluronic acid (HA) production process as an HA precipitating agent. 3-(Trimethoxysilyl)-propyldimethyloctadecyl ammonium chloride, a Si containing QAC (Si-QAC) generally used to modify the surface of cotton fibers for the preparation of nonleaching antibacterial textiles, has a chemical structure very similar to CPC. Choline, a natural QAC, can form a deep eutectic solvent with urea and be grafted onto cotton surface when incubating cotton in the deep eutectic solvent. Both of the QAC-modified cottons demonstrated antibacterial activity against Gram (-) Escherichia coli and Gram (+) Bacillus subtilis along with HA adsorption capacity. The HA adsorption isotherm could be well-fitted with Langmuir model with maximum adsorption capacities of 184. mg/g and 351. mg/g for Si-QAC and choline surface-functionalized cotton fibers, respectively. In the presence of high concentration of contaminants, HA could be directly recovered from a B. subtilis culture with a capacity of 15. mg/g by using Si-QAC modified antimicrobial cotton fiber.
Keyword Adsorption
Deep eutectic solvent
Hyaluronic acid
Hydrophobic interaction
Quaternary ammonium
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
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Created: Thu, 14 May 2015, 18:36:03 EST by David Wibowo on behalf of Aust Institute for Bioengineering & Nanotechnology