Multidrug-resistant Escherichia coli in Asia: epidemiology and management

Sidjabat, Hanna E. and Paterson, David L. (2015) Multidrug-resistant Escherichia coli in Asia: epidemiology and management. Expert Review of Anti-Infective Therapy, 13 5: 575-591. doi:10.1586/14787210.2015.1028365


Author Sidjabat, Hanna E.
Paterson, David L.
Title Multidrug-resistant Escherichia coli in Asia: epidemiology and management
Formatted title
Multidrug-resistant Escherichia coli in Asia: epidemiology and management
Journal name Expert Review of Anti-Infective Therapy   Check publisher's open access policy
ISSN 1744-8336
1478-7210
Publication date 2015-05-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1586/14787210.2015.1028365
Open Access Status Not yet assessed
Volume 13
Issue 5
Start page 575
End page 591
Total pages 17
Place of publication London, United Kingdom
Publisher Expert Reviews
Collection year 2016
Language eng
Formatted abstract
Escherichia coli has become multiresistant by way of production of a variety of β-lactamases. The prevalence of CTX-M–producing E. coli has reached 60–79% in certain parts of Asia. The acquisition of CTX-M plasmids by E. coli sequence type 131, a successful clone of E. coli, has caused further dissemination of CTX-M–producing E. coli. The prevalence of carbapenemase-producing E. coli, especially Klebsiella pneumoniae carbapenemase, and New Delhi metallo-β-lactamase (NDM)-producing E. coli has been increasing in Asia. K. pneumoniae carbapenemase and NDM have now been found in E. coli sequence type 131. The occurrence of NDM-producing E. coli is a major concern particularly in the Indian subcontinent, but now elsewhere in Asia as well. There are multiple reasons why antibiotic resistance in E. coli in Asia has reached such extreme levels. Approaches beyond antibiotic therapy, such as prevention of antibiotic resistance by antibiotic stewardship and protecting natural microbiome, are strategies to avoid further spread of antibiotic resistance.
Keyword AmpC
Asia
Carbapenemase
ESBL
Management
Molecular epidemiology
Multidrug-resistant Escherichia coli
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: UQ Centre for Clinical Research Publications
Official 2016 Collection
 
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Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
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