Cytomegalovirus disease in immunocompetent adults

Lancini, Daniel, Faddy, Helen M., Flower, Robert and Hogan, Chris (2014) Cytomegalovirus disease in immunocompetent adults. The Medical Journal of Australia, 201 10: 578-580. doi:10.5694/mja14.00183

Attached Files (Some files may be inaccessible until you login with your UQ eSpace credentials)
Name Description MIMEType Size Downloads

Author Lancini, Daniel
Faddy, Helen M.
Flower, Robert
Hogan, Chris
Title Cytomegalovirus disease in immunocompetent adults
Journal name The Medical Journal of Australia   Check publisher's open access policy
ISSN 1326-5377
Publication date 2014-11-17
Year available 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.5694/mja14.00183
Open Access Status Not yet assessed
Volume 201
Issue 10
Start page 578
End page 580
Total pages 3
Place of publication Strawberry Hills, NSW, Australia
Publisher Australasian Medical Publishing Company
Language eng
Formatted abstract
Cytomegalovirus (CMV) is a highly prevalent and globally distributed virus.

CMV infection in healthy adults is usually asymptomatic or causes a mild mononucleosis-like syndrome.

CMV disease causes significant morbidity and mortality in neonates and severely immunocompromised adults.

CMV disease can present with a wide range of manifestations, with colitis being the most common.

The incidence of severe CMV disease in immunocompetent adults appears to be greater than previously thought, which may be partly due to immune dysfunction related to comorbidities such as kidney disease or diabetes mellitus.

CMV disease can mimic an array of alternative diagnoses and pose a significant diagnostic challenge, especially in immunocompetent adults, leading to delayed diagnosis, adverse health outcomes and unnecessary financial expense.

Non-invasive testing for CMV is widely available and can facilitate early diagnosis if used appropriately.

Although limited, current evidence suggests that targeted antiviral therapy with ganciclovir or valganciclovir is appropriate for severe CMV disease in immunocompetent adults.
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Non HERDC
Official Audit
School of Medicine Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 20 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 26 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 07 Apr 2015, 11:59:05 EST by System User on behalf of School of Medicine