Clostridium difficile infection seasonality: Patterns across hemispheres and continents - A systematic review

Furuya-Kanamori, Luis, McKenzie, Samantha J., Yakob, Laith, Clark, Justin, Paterson, David L., Riley, Thomas V. and Clements, Archie C. (2015) Clostridium difficile infection seasonality: Patterns across hemispheres and continents - A systematic review. PLoS One, 10 3: . doi:10.1371/journal.pone.0120730


Author Furuya-Kanamori, Luis
McKenzie, Samantha J.
Yakob, Laith
Clark, Justin
Paterson, David L.
Riley, Thomas V.
Clements, Archie C.
Title Clostridium difficile infection seasonality: Patterns across hemispheres and continents - A systematic review
Formatted title
Clostridium difficile Infection Seasonality: Patterns across Hemispheres and Continents – A Systematic Review
Journal name PLoS One   Check publisher's open access policy
ISSN 1932-6203
Publication date 2015-03-16
Year available 2015
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1371/journal.pone.0120730
Open Access Status DOI
Volume 10
Issue 3
Total pages 12
Place of publication San Francisco, CA United States
Publisher Public Library of Science
Language eng
Formatted abstract
Background
Studies have demonstrated seasonal variability in rates of Clostridium difficile infection (CDI). Synthesising all available information on seasonality is a necessary step in identifying large-scale epidemiological patterns and elucidating underlying causes.

Methods
Three medical and life sciences publication databases were searched from inception to October 2014 for longitudinal epidemiological studies written in English, Spanish or Portuguese that reported the incidence of CDI. The monthly frequency of CDI were extracted, standardized and weighted according to the number of follow-up months. Cross correlation coefficients (XCORR) were calculated to examine the correlation and lag between the year-month frequencies of reported CDI across hemispheres and continents.

Results
The search identified 13, 5 and 2 studies from North America, Europe, and Oceania, respectively that met the inclusion criteria. CDI had a similar seasonal pattern in the Northern and Southern Hemisphere characterized by a peak in spring and lower frequencies of CDI in summer/autumn with a lag of 8 months (XCORR = 0.60) between hemispheres. There was no difference between the seasonal patterns across European and North American countries.

Conclusion
CDI demonstrates a distinct seasonal pattern that is consistent across North America, Europe and Oceania. Further studies are required to identify the driving factors of the observed seasonality.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: UQ Centre for Clinical Research Publications
Official 2016 Collection
School of Public Health Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 5 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 7 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 31 Mar 2015, 10:20:09 EST by System User on behalf of School of Public Health