Centipede venom: Recent discoveries and current state of knowledge

Undheim, Eivind, Fry, Bryan and King, Glenn F (2015) Centipede venom: Recent discoveries and current state of knowledge. Toxins, 7 3: 679-704. doi:10.3390/toxins7030679

Author Undheim, Eivind
Fry, Bryan
King, Glenn F
Title Centipede venom: Recent discoveries and current state of knowledge
Journal name Toxins   Check publisher's open access policy
ISSN 2072-6651
Publication date 2015-02-25
Year available 2015
Sub-type Article (original research)
DOI 10.3390/toxins7030679
Open Access Status DOI
Volume 7
Issue 3
Start page 679
End page 704
Total pages 26
Place of publication Basel, Switzerland
Publisher M D P I
Language eng
Subject 3005 Toxicology
2307 Health, Toxicology and Mutagenesis
Abstract Centipedes are among the oldest extant venomous predators on the planet. Armed with a pair of modified, venom-bearing limbs, they are an important group of predatory arthropods and are infamous for their ability to deliver painful stings. Despite this, very little is known about centipede venom and its composition. Advances in analytical tools, however, have recently provided the first detailed insights into the composition and evolution of centipede venoms. This has revealed that centipede venom proteins are highly diverse, with 61 phylogenetically distinct venom protein and peptide families. A number of these have been convergently recruited into the venoms of other animals, providing valuable information on potential underlying causes of the occasionally serious complications arising from human centipede envenomations. However, the majority of venom protein and peptide families bear no resemblance to any characterised protein or peptide family, highlighting the novelty of centipede venoms. This review highlights recent discoveries and summarises the current state of knowledge on the fascinating venom system of centipedes.
Keyword Centipede venom
Q-Index Code C1
Q-Index Status Confirmed Code
Grant ID DP130103813
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Biological Sciences Publications
Institute for Molecular Bioscience - Publications
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Citation counts: TR Web of Science Citation Count  Cited 14 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 16 times in Scopus Article | Citations
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Created: Fri, 27 Mar 2015, 00:22:56 EST by Susan Allen on behalf of Institute for Molecular Bioscience