In vitro evaluation of an ultrasonic cardiac output monitoring (USCOM) device

Gregory, Shaun D, Cooney, Helena, Diab, Sara., Anstey, Chris, Thom, Ogilvie and Fraser, John F (2015) In vitro evaluation of an ultrasonic cardiac output monitoring (USCOM) device. Journal of Clinical Monitoring and Computing, 30 1: 69-75. doi:10.1007/s10877-015-9685-8

Author Gregory, Shaun D
Cooney, Helena
Diab, Sara.
Anstey, Chris
Thom, Ogilvie
Fraser, John F
Title In vitro evaluation of an ultrasonic cardiac output monitoring (USCOM) device
Journal name Journal of Clinical Monitoring and Computing   Check publisher's open access policy
ISSN 1573-2614
Publication date 2015-03-07
Year available 2015
Sub-type Article (original research)
DOI 10.1007/s10877-015-9685-8
Open Access Status Not yet assessed
Volume 30
Issue 1
Start page 69
End page 75
Total pages 7
Place of publication Dordrecht, Netherlands
Publisher Springer Netherlands
Language eng
Subject 2718 Health Informatics
2706 Critical Care and Intensive Care Medicine
2703 Anesthesiology and Pain Medicine
Abstract Non-invasive cardiac output monitoring techniques provide high yield, low risk mechanisms to identify and individually treat shock in the emergency setting. The non-invasive ultrasonic cardiac output monitoring (USCOM) device uses an ultrasound probe applied externally to the chest; however limitations exist with previous validation strategies. This study presents the in vitro validation of the USCOM device against calibrated flow sensors and compares user variability in simulated healthy and septic conditions. A validated mock circulation loop was used to simulate each condition with a range of cardiac outputs (2–10 l/min) and heart rates (50–95 bpm). Three users with varying degrees of experience using the USCOM device measured cardiac output and heart rate by placing the ultrasound probe on the mock aorta. Users were blinded to the condition, heart rate and cardiac output which were randomly generated. Results were reported as linear regression slope (β). All users estimated heart rate in both conditions with reasonable accuracy (β = 0.86–1.01), while cardiac output in the sepsis condition was estimated with great precision (β = 1.03–1.04). Users generally overestimated the cardiac output in the healthy simulation (β = 1.07–1.26) and reported greater difficulty estimating reduced cardiac output compared with higher values. Although there was some variability between users, particularly in the healthy condition (P < 0.01), all estimations were within a clinically acceptable range. In this study the USCOM provided a suitable measurement of cardiac output and heart rate when compared with our in vitro system. It is a promising technique to assist with the identification and treatment of shock.
Keyword USCOM
Cardiac output
Mock circulation loop
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Medicine Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 1 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 4 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 24 Mar 2015, 10:51:01 EST by System User on behalf of Scholarly Communication and Digitisation Service