Rapid induction of omega-3 fatty acids (EPA) in Nannochloropsis sp. by UV-C radiation

Sharma, Kalpesh and Schenk, Peer M. (2015) Rapid induction of omega-3 fatty acids (EPA) in Nannochloropsis sp. by UV-C radiation. Biotechnology and Bioengineering, 112 6: 1243-1249. doi:10.1002/bit.25544


Author Sharma, Kalpesh
Schenk, Peer M.
Title Rapid induction of omega-3 fatty acids (EPA) in Nannochloropsis sp. by UV-C radiation
Formatted title
Rapid induction of omega-3 fatty acids (EPA) in Nannochloropsis sp. by UV-C radiation
Journal name Biotechnology and Bioengineering   Check publisher's open access policy
ISSN 1097-0290
0006-3592
Publication date 2015-06-01
Year available 2015
Sub-type Article (original research)
DOI 10.1002/bit.25544
Volume 112
Issue 6
Start page 1243
End page 1249
Total pages 7
Place of publication Hoboken NJ, United States
Publisher John Wiley & Sons
Language eng
Formatted abstract
Omega-3 fatty acids, such as eicosapentaenoic acid (EPA), provide substantial health benefits. As global fish stocks are declining and in some cases are contaminated with heavy metals, there is a need to find more sustainable land-based sources of these essential fatty acids. The oleaginous microalga Nannochloropsis sp. has been identified as a highly efficient producer of omega-3 fatty acids. In this study, we present a new process to rapidly induce biosynthesis of essential fatty acids, including EPA in Nannochloropsis sp. BR2. Short exposure to UV-C at a dose of 100 or 250 mJ/cm2 led to a significant increase in total cellular lipid contents when compared to mock-treated controls. A low dosage of 100 mJ/cm2 also led to a twofold increase in total EPA content within 24 h that constituted 30% of total fatty acids and up to 12% of total dry weight at higher dosages. UV-C radiation may find uses as an easily applicable external inducer for large-scale production of omega-3 production from microalgae.
Keyword EPA
Microalgae
Nannochloropsis
Omega-3 fatty acids
PUFA
UV-C
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Agriculture and Food Sciences
Official 2016 Collection
 
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