Topographic wiring of the retinotectal connection in zebrafish

Kita, Elizabeth M, Scott, Ethan K and Goodhill, Geoffrey J (2015) Topographic wiring of the retinotectal connection in zebrafish. Developmental Neurobiology, 75 6: 542-556. doi:10.1002/dneu.22256


Author Kita, Elizabeth M
Scott, Ethan K
Goodhill, Geoffrey J
Title Topographic wiring of the retinotectal connection in zebrafish
Journal name Developmental Neurobiology   Check publisher's open access policy
ISSN 1932-846X
1932-8451
Publication date 2015-01-14
Year available 2015
Sub-type Article (original research)
DOI 10.1002/dneu.22256
Volume 75
Issue 6
Start page 542
End page 556
Total pages 15
Place of publication Hoboken, United States
Publisher John Wiley & Sons, Inc
Collection year 2016
Language eng
Subject 2804 Cellular and Molecular Neuroscience
2806 Developmental Neuroscience
Abstract The zebrafish retinotectal projection provides an attractive model system for studying many aspects of topographic map formation and maintenance. Visual connections initially start to form between 3 and 5 days postfertilization, and remain plastic throughout the life of the fish. Zebrafish are easily manipulated surgically, genetically, and chemically, and a variety of molecular tools exist to enable visualization and control of various aspects of map development. Here, we review zebrafish retinotectal map formation, focusing particularly on the detailed structure and dynamics of the connections, the molecules that are important in map creation, and how activity regulates the maintenance of the map.
Keyword Zebrafish
Retinotectal map
Tectum
RGC
Development
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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