Antibacterial activity of fluoride compounds and herbal toothpastes on Streptococcus mutans: an in vitro study

Randall, J., Seow, W. K. and Walsh, L. J. (2015) Antibacterial activity of fluoride compounds and herbal toothpastes on Streptococcus mutans: an in vitro study. Australian Dental Journal, 60 3: 368-374. doi:10.1111/adj.12247


Author Randall, J.
Seow, W. K.
Walsh, L. J.
Title Antibacterial activity of fluoride compounds and herbal toothpastes on Streptococcus mutans: an in vitro study
Formatted title
Antibacterial activity of fluoride compounds and herbal toothpastes on Streptococcus mutans: an in vitro study
Journal name Australian Dental Journal   Check publisher's open access policy
ISSN 1834-7819
0045-0421
Publication date 2015-09-01
Sub-type Article (original research)
DOI 10.1111/adj.12247
Volume 60
Issue 3
Start page 368
End page 374
Total pages 16
Place of publication Chichester, West Sussex, United Kingdom
Publisher Wiley-Blackwell Publishing
Language eng
Formatted abstract
Background
Streptococcus mutans is an important bacterial species implicated in dental caries. This laboratory study compared the antimicrobial activity of a number of fluoride-containing and herbal dentifrices and their components against S. mutans.

Methods
An agar diffusion method was used with Mueller-Hinton agar. Wells were filled with either 10 commercial fluoride or 6 herbal dentifrices, or with solutions of various fluoride compounds, sodium lauryl sulphate, sodium benzoate, chlorhexidine digluconate or triclosan. Diameters of zones of bacterial growth inhibition surrounding the wells were measured using a micrometer.

Results
Significant differences were found for growth inhibition between the 10 fluoridated dentifrices (P<0.0001), with Colgate Total having the greatest effect. There was not a direct correlation with fluoride type or fluoride concentration. The antibacterial activities of the 6 herbal toothpastes varied, with Herbal Fresh being the strongest. Sodium lauryl sulphate showed strong antimicrobial activity against S. mutans at the levels used in dentifrices.

Conclusions
Antimicrobial activity of commercial dentifrices against S. mutans may be exerted by components other than fluoride. Ingredients such as triclosan and sodium lauryl sulphate have larger antimicrobial effects than fluorides in this model.
Keyword Toothpaste
Fluoride
Herbal
Antibacterial
Streptococcus mutans
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Dentistry Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
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Created: Thu, 19 Feb 2015, 02:39:54 EST by Professor Laurence Walsh on behalf of School of Dentistry