High Caloric diets for amyotrophic lateral sclerosis

Ngo, Shyuan T., Steyn, Frederik J., McCombe, Pamela A. and Borges, Karin (2015). High Caloric diets for amyotrophic lateral sclerosis. In Ronald Ross Watson and Victor R. Preedy (Ed.), Bioactive nutraceuticals and dietary supplements in neurological and brain disease: prevention and therapy (pp. 355-361) London, United Kingdom: Academic Press. doi:10.1016/B978-0-12-411462-3.00036-9

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Author Ngo, Shyuan T.
Steyn, Frederik J.
McCombe, Pamela A.
Borges, Karin
Title of chapter High Caloric diets for amyotrophic lateral sclerosis
Title of book Bioactive nutraceuticals and dietary supplements in neurological and brain disease: prevention and therapy
Language of Book Title eng
Place of Publication London, United Kingdom
Publisher Academic Press
Publication Year 2015
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/B978-0-12-411462-3.00036-9
Open Access Status
Year available 2015
ISBN 9780124114623
Editor Ronald Ross Watson
Victor R. Preedy
Chapter number 36
Start page 355
End page 361
Total pages 7
Total chapters 50
Language eng
Subjects 2700 Medicine
Abstract/Summary Amyotrophic lateral scelrosis (ALS) is a fatal neurodegenerative disease. Over the years, studies have described the negative impact of malnutrition and weight loss on disease progression and survival. This in turn has highlighted the critical importance of the need to manage adequate nutrition and to maintain body weight in ALS patients during the course of disease. In recent years, dietary supplementation with nutraceuticals has become popular among ALS patients. Although the beneficial outcomes of nutraceuticals in ALS are yet to be elucidated, the benefits of alternative dietary regimens have been assessed in ALS mouse models and in ALS patients. Current evidence from studies that have investigated the effects of a high-protein, high-carbohydrate, high-fat, or ketogenic diet in ALS appear to support the notion that supplementation with a high-fat diet is most beneficial because it reduces ALS risk and provides positive survival outcomes in ALS.
Keyword Amyotrophic lateral sclerosis
Weight loss
High-calorie diets
High-fat diets
Q-Index Code B1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Figures,Color plates

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Created: Mon, 19 Jan 2015, 19:48:50 EST by Dr Karin Borges on behalf of School of Biomedical Sciences