Symptom screening scales for detecting major depressive disorder in children and adolescents: A systematic review and meta-analysis of reliability, validity and diagnostic utility

Stockings, Emily, Degenhardt, Louisa, Lee, Yong Yi, Mihalopoulos, Cathrine, Liu, Angus, Hobbs, Megan and Patton, George (2015) Symptom screening scales for detecting major depressive disorder in children and adolescents: A systematic review and meta-analysis of reliability, validity and diagnostic utility. Journal of Affective Disorders, 174 447-463. doi:10.1016/j.jad.2014.11.061

Attached Files (Some files may be inaccessible until you login with your UQ eSpace credentials)
Name Description MIMEType Size Downloads
UQ348925_OA.pdf Full text (open access) application/pdf 615.97KB 0

Author Stockings, Emily
Degenhardt, Louisa
Lee, Yong Yi
Mihalopoulos, Cathrine
Liu, Angus
Hobbs, Megan
Patton, George
Title Symptom screening scales for detecting major depressive disorder in children and adolescents: A systematic review and meta-analysis of reliability, validity and diagnostic utility
Journal name Journal of Affective Disorders   Check publisher's open access policy
ISSN 1573-2517
0165-0327
Publication date 2015-03-01
Year available 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.jad.2014.11.061
Open Access Status File (Author Post-print)
Volume 174
Start page 447
End page 463
Total pages 17
Place of publication Amsterdam, Netherlands
Publisher Elsevier BV
Language eng
Subject 3203 Clinical Psychology
2738 Psychiatry and Mental health
Abstract Background Depression symptom screening scales are often used to determine a clinical diagnosis of major depressive disorder (MDD) in prevention research. The aim of this review is to systematically examine the reliability, validity and diagnostic utility of commonly used screening scales in depression prevention research among children and adolescents.
Formatted abstract
Background
Depression symptom screening scales are often used to determine a clinical diagnosis of major depressive disorder (MDD) in prevention research. The aim of this review is to systematically examine the reliability, validity and diagnostic utility of commonly used screening scales in depression prevention research among children and adolescents.

Methods
We conducted a systematic review of the electronic databases PsycINFO, PsycEXTRA and Medline examining the reliability, validity and diagnostic utility of four commonly used depression symptom rating scales among children and adolescents: the Children׳s Depression Inventory (CDI), Beck Depression Inventory (BDI), Center for Epidemiologic Studies – Depression Scale (CES-D) and the Reynolds Adolescent Depression Scale (RADS). We used univariate and bivariate random effects models to pool data and conducted metaregression to identify and explain causes of heterogeneity.

Results
We identified 54 studies (66 data points, 34,542 participants). Across the four scales, internal reliability was ‘good’ (pooled estimate: 0.89, 95% Confidence Interval (CI): 0.86–0.92). Sensitivity and specificity were ‘moderate’ (sensitivity: 0.80, 95% CI: 0.76–0.84; specificity: 0.78, 95% CI: 0.74–0.83). For studies that used a diagnostic interview to determine a diagnosis of MDD, positive predictive power for identifying true cases was mostly poor. Psychometric properties did not differ on the basis of study quality, sample type (clinical vs. nonclinical) or sample age (child vs. adolescent).

Limitations
Some analyses may have been underpowered to identify conditions in which test performance may vary, due to low numbers of studies with adequate data.

Conclusions
Commonly used depression symptom rating scales are reliable measures of depressive symptoms among adolescents; however, using cutoff scores to indicate clinical levels of depression may result in many false positives.
Keyword Children and adolescents
Depression
Prevention
Psychiatric Symptom Rating Scales
Psychometrics
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2015 Collection
School of Public Health Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 38 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 40 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 13 Jan 2015, 10:15:55 EST by System User on behalf of School of Public Health