Recovery From Directional Hypokinesia and Bradykinesia in Unilateral Neglect

Mattingley, JB, Bradshaw, JL, Bradshaw, JA and Nettleton, NC (1994) Recovery From Directional Hypokinesia and Bradykinesia in Unilateral Neglect. Journal of Clinical and Experimental Neuropsychology, 16 6: 861-876. doi:10.1080/01688639408402699

Author Mattingley, JB
Bradshaw, JL
Bradshaw, JA
Nettleton, NC
Title Recovery From Directional Hypokinesia and Bradykinesia in Unilateral Neglect
Journal name Journal of Clinical and Experimental Neuropsychology   Check publisher's open access policy
ISSN 1380-3395
Publication date 1994-12-01
Year available 1994
Sub-type Article (original research)
DOI 10.1080/01688639408402699
Open Access Status Not yet assessed
Volume 16
Issue 6
Start page 861
End page 876
Total pages 16
Place of publication LISSE
Language eng
Abstract Patients with acute right hemisphere (RH) damage and left unilateral neglect may exhibit slowness in both the initiation and execution of goal-directed movements toward the contralesional side (respectively, directional hypokinesia and directional bradykinesia). We retested 13 patients with RH damage, who on initial testing 1 year earlier had shown these impairments on a visually cued sequential movement task. Initiation and execution times were measured separately for leftward and rightward movement sequences, performed in either hemispace and across the body midline. Patients with anterior/subcortical lesions exhibited directional hypokinesia and bradykinesia on initial testing, but no longer showed either after 12 months. It is suggested that the recovery exhibited by these patients was determined conjointly by residual functioning of flexible anterior/subcortical structures involved in response production, in addition to the resolution of transient secondary dysfunction (i.e., diaschisis) of posterior (parietal) areas responsible for attentional orienting and target selection. In contrast, patients with posterior (parietal) lesions continued to exhibit directional hypokinesia after 12 months, probably as a result of permament damage to a region whose dedicated or specialised functions cannot readily be compensated by other brain areas. These results support the notion that spatial attention and goal-directed movement are subserved by a distributed network involving separate but interconnected brain regions. Distinct functional losses may be predicted, in both the acute and chronic stages postinjury, on the basis of temporary or permanent dysfunction of discrete components of this network.
Keyword Right-Hemisphere Stroke
Directed Attention
Subcortical Stroke
Cerebral Perfusion
Covert Attention
Visual Neglect
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: ResearcherID Downloads - Archived
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