The epidemiology and global burden of autism spectrum disorders

Baxter, A. J., Brugha, T. S., Erskine, H. E., Scheurer, R. W., Vos, T. and Scott, J. G. (2015) The epidemiology and global burden of autism spectrum disorders. Psychological Medicine, 45 3: 601-613. doi:10.1017/S003329171400172X


Author Baxter, A. J.
Brugha, T. S.
Erskine, H. E.
Scheurer, R. W.
Vos, T.
Scott, J. G.
Title The epidemiology and global burden of autism spectrum disorders
Journal name Psychological Medicine   Check publisher's open access policy
ISSN 0033-2917
1469-8978
Publication date 2015-02-01
Year available 2014
Sub-type Article (original research)
DOI 10.1017/S003329171400172X
Volume 45
Issue 3
Start page 601
End page 613
Total pages 13
Place of publication Cambridge, United Kingdom
Publisher Cambridge University Press
Collection year 2015
Language eng
Formatted abstract
Background: Autism spectrum disorders (ASDs) are persistent disabling neurodevelopmental disorders clinically evident
from early childhood. For the first time, the burden of ASDs has been estimated for the Global Burden of Disease Study 2010 (GBD 2010). The aims of this study were to develop global and regional prevalence models and estimate the global burden of disease of ASDs.

Method: A systematic review was conducted for epidemiological data (prevalence, incidence, remission and mortality risk) of autistic disorder and other ASDs. Data were pooled using a Bayesian meta-regression approach while adjusting for between-study variance to derive prevalence models. Burden was calculated in terms of years lived with disability (YLDs) and disability-adjusted life-years (DALYs), which are reported here by world region for 1990 and 2010.

Results: In 2010 there were an estimated 52 million cases of ASDs, equating to a prevalence of 7.6 per 1000 or one in 132 persons. After accounting for methodological variations, there was no clear evidence of a change in prevalence for autistic disorder or other ASDs between 1990 and 2010. Worldwide, there was little regional variation in the prevalence of ASDs. Globally, autistic disorders accounted for more than 58 DALYs per 100 000 population and other ASDs accounted for 53 DALYs per 100 000.

Conclusions: ASDs account for substantial health loss across the lifespan. Understanding the burden of ASDs is essential for effective policy making. An accurate epidemiological description of ASDs is needed to inform public health policy and to plan for education, housing and financial support services.
Keyword Asperger’s disorder
Autism
Autistic Spectrum Disorders
Burden of disease
Epidemiological study
Epidemiology
Global health
Mental disorders
Prevalence
Public health
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Online publication: 1 August 2014.

 
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Created: Tue, 06 Jan 2015, 01:30:10 EST by Amanda Baxter on behalf of Aboriginal and Torres Strait Islander Studies Unit