Toxoplasma gondii tachyzoite-bradyzoite interconversion

Lyons, RE, McLeod, R and Roberts, CW (2002) Toxoplasma gondii tachyzoite-bradyzoite interconversion. Trends in Parasitology, 18 5: 198-201. doi:10.1016/S1471-4922(02)02248-1


Author Lyons, RE
McLeod, R
Roberts, CW
Title Toxoplasma gondii tachyzoite-bradyzoite interconversion
Journal name Trends in Parasitology   Check publisher's open access policy
ISSN 1471-4922
Publication date 2002-05-01
Year available 2002
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/S1471-4922(02)02248-1
Open Access Status Not yet assessed
Volume 18
Issue 5
Start page 198
End page 201
Total pages 4
Publisher ELSEVIER SCI LTD
Language eng
Subject 2725 Infectious Diseases
2405 Parasitology
Abstract During infection in the intermediate host, Toxoplasma gondii undergoes stage conversion between the rapidly dividing tachyzoite that is responsible for acute toxoplasmosis and the slowly replicating, encysted bradyzoite stage. This process of tachyzoite-bradyzoite interconversion is central to the pathogenesis and longevity of infection. Recent research has identified several stage-specific genes and proteins. However, despite recent advances in the understanding of Toxoplasma cell biology, more research is necessary to elucidate the complex events occurring during tachyzoite-bradyzoite interconversion. Here, a brief summary of this process is provided and a new method to characterize gene expression during interconversion is introduced.
Keyword Parasitology
Parasitology
PARASITOLOGY
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID R01 AI-IMP44572
Institutional Status Unknown

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: ResearcherID Downloads - Archived
 
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