EQ-5D-3L derived population norms for health related quality of life in Sri Lanka

Kularatna, Sanjeewa, Whitty, , Jennifer A., Johnson, Newell W., Jayasinghe, Ruwan and Scuffham, Paul A (2014) EQ-5D-3L derived population norms for health related quality of life in Sri Lanka. PLoS One, 9 11: e108434.1-e108434.12. doi:10.1371/journal.pone.0108434

Author Kularatna, Sanjeewa
Whitty, , Jennifer A.
Johnson, Newell W.
Jayasinghe, Ruwan
Scuffham, Paul A
Title EQ-5D-3L derived population norms for health related quality of life in Sri Lanka
Journal name PLoS One   Check publisher's open access policy
ISSN 1932-6203
Publication date 2014-11-03
Year available 2014
Sub-type Article (original research)
DOI 10.1371/journal.pone.0108434
Open Access Status DOI
Volume 9
Issue 11
Start page e108434.1
End page e108434.12
Total pages 12
Place of publication San Francisco, CA United States
Publisher Public Library of Science
Collection year 2015
Language eng
Formatted abstract
Background: Health Related Quality of Life (HRQoL) is an important outcome measure in health economic evaluation that
guides health resource allocations. Population norms for HRQoL are an essential ingredient in health economics and in the
evaluation of population health. The aim of this study was to produce EQ-5D-3L-derived population norms for Sri Lanka.

Method: A population sample (n = 780) was selected from four districts of Sri Lanka. A stratified cluster sampling approach
with probability proportionate to size was employed. Twenty six clusters of 30 participants each were selected; each
participant completed the EQ-5D-3L in a face-to-face interview. Utility weights for their EQ-5D-3L health states were
assigned using the Sri Lankan EQ-5D-3L algorithm. The population norms are reported by age and socio-economic

Results: The EQ-5D-3L was completed by 736 people, representing a 94% response rate. Sixty per cent of the sample
reported being in full health. The percentage of people responding to any problems in the five EQ-5D-3L dimensions
increased with age. The mean EQ-5D-3L weight was 0.85 (SD 0.008; 95%CI 0.84-0.87). The mean EQ-5D-3L weight was
significantly associated with age, housing type, disease experience and religiosity. People above 70 years of age were 7.5
times more likely to report mobility problems and 3.7 times more likely to report pain/discomfort than those aged 18-29
years. Those with a tertiary education were five times less likely to report any HRQoL problems than those without a tertiary
education. A person living in a shanty was 4.3 more likely to have problems in usual activities than a person living in a single

Conclusion: The population norms in Sri Lanka vary with socio-demographic characteristics. The socioeconomically
disadvantaged have a lower HRQoL. The trends of population norms observed in this lower middle income country were
generally similar to those previously reported in high income countries.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Pharmacy Publications
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