Stereotactic body radiotherapy for spinal metastases: current status, with a focus on its application in the postoperative patient. A review

Sahgal, Arjun, Bilsky, Mark, Chang, Eric L., Ma, Lijun, Yamada, Yoshiya, Rhines, Laurence D., Letourneau, Daniel, Foote, Matthew, Yu, Eugene, Larson, David A. and Fehlings, Michael G. (2011) Stereotactic body radiotherapy for spinal metastases: current status, with a focus on its application in the postoperative patient. A review. Journal of Neurosurgery: Spine, 14 2: 151-166. doi:10.3171/2010.9.SPINE091005


Author Sahgal, Arjun
Bilsky, Mark
Chang, Eric L.
Ma, Lijun
Yamada, Yoshiya
Rhines, Laurence D.
Letourneau, Daniel
Foote, Matthew
Yu, Eugene
Larson, David A.
Fehlings, Michael G.
Title Stereotactic body radiotherapy for spinal metastases: current status, with a focus on its application in the postoperative patient. A review
Journal name Journal of Neurosurgery: Spine   Check publisher's open access policy
ISSN 1547-5654
1547-5646
Publication date 2011-02-01
Year available 2011
Sub-type Critical review of research, literature review, critical commentary
DOI 10.3171/2010.9.SPINE091005
Open Access Status Not yet assessed
Volume 14
Issue 2
Start page 151
End page 166
Total pages 16
Place of publication Rolling Meadows, IL, United States
Publisher American Association of Neurological Surgeons
Language eng
Abstract Stereotactic body radiotherapy (SBRT) for spinal metastases is an emerging therapeutic option aimed at delivering high biologically effective doses to metastases while sparing the adjacent normal tissues. This technique has emerged following advances in radiation delivery that include sophisticated radiation treatment planning software, body immobilization devices, and capabilities of detecting and correcting patient positional deviations with imageguided radiotherapy. There are limited clinical data specifically supporting the role of SBRT as a superior alternative to conventional radiation in the postoperative patient. The focus of this review was to examine the evidence pertaining to spine SBRT in the treatment of spinal metastases and to provide a comprehensive analysis of published patterns of failure, with emphasis on the postoperative patient.
Keyword Malignant epidural spinal cord compression
Postoperative radiation
Spinal metastasis
Spine radiosurgery
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: UQ Diamantina Institute Publications
 
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