The benefits and harms of deprescribing

Reeve, Emily, Shakib, Sepehr, Hendrix, Ivanka, Roberts, Michael S. and Wiese, Michael D. (2014) The benefits and harms of deprescribing. Medical Journal of Australia, 201 7: 386-389. doi:10.5694/mja13.00200

Author Reeve, Emily
Shakib, Sepehr
Hendrix, Ivanka
Roberts, Michael S.
Wiese, Michael D.
Title The benefits and harms of deprescribing
Journal name Medical Journal of Australia   Check publisher's open access policy
ISSN 0025-729X
Publication date 2014-10-06
Year available 2014
Sub-type Article (original research)
DOI 10.5694/mja13.00200
Open Access Status
Volume 201
Issue 7
Start page 386
End page 389
Total pages 4
Place of publication Strawberry Hills, NSW Australia
Publisher Australasian Medical Publishing
Language eng
Formatted abstract
As people age there tends to be an increase in their number of comorbidities and, consequently, an increase in the number of medications they take. With Australia’s ageing population, concerns regarding polypharmacy, such as increased risk of adverse drug reactions (ADRs) and financial costs, are set to rise.1 While polypharmacy is appropriate in many individuals,
up to 60% of older people are exposed to inappropriate medication use (IMU; ie, use of a medication when the harms outweigh the benefits in an individual). Medications that may initially have been appropriately prescribed can, with ageing and new medical conditions, become inappropriate.2 Evidence to date indicates that ceasing use of medication is at least as complicated as initiating treatment, and the term “deprescribing” was coined to describe the complex process that is required.1 Deprescribing has the potential to greatly improve health outcomes through stopping or reducing the dose of inappropriate medications; but, currently, concrete evidence regarding its effect is equivocal. In addition, deprescribing
is not free from harm, and the potential adverse consequences of medication withdrawal must therefore be considered.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 17 times in Thomson Reuters Web of Science Article | Citations
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