Antibiotic-resistant genes and antibiotic-resistant bacteria in the effluent of urban residential areas, hospitals, and a municipal wastewater treatment plant system

Li, Jianan, Cheng, Weixiao, Xu, Like, Strong, P. J. and Chen, Hong (2014) Antibiotic-resistant genes and antibiotic-resistant bacteria in the effluent of urban residential areas, hospitals, and a municipal wastewater treatment plant system. Environmental Science and Pollution Research, 22 6: 4587-4596. doi:10.1007/s11356-014-3665-2


Author Li, Jianan
Cheng, Weixiao
Xu, Like
Strong, P. J.
Chen, Hong
Title Antibiotic-resistant genes and antibiotic-resistant bacteria in the effluent of urban residential areas, hospitals, and a municipal wastewater treatment plant system
Journal name Environmental Science and Pollution Research   Check publisher's open access policy
ISSN 1614-7499
0944-1344
Publication date 2014-10-18
Year available 2014
Sub-type Article (original research)
DOI 10.1007/s11356-014-3665-2
Open Access Status
Volume 22
Issue 6
Start page 4587
End page 4596
Total pages 10
Place of publication Heidelberg Germany
Publisher Springer
Language eng
Formatted abstract
In this study, we determined the abundance of 8 antibiotics (3 tetracyclines, 4 sulfonamides, and 1 trimethoprim), 12 antibiotic-resistant genes (10 tet, 2 sul), 4 antibiotic-resistant bacteria (tetracycline, sulfamethoxazole, and combined resistance), and class 1 integron integrase gene (intI1) in the effluent of residential areas, hospitals, and municipal wastewater treatment plant (WWTP) systems. The concentrations of total/individual targets (antibiotics, genes, and bacteria) varied remarkably among different samples, but the hospital samples generally had a lower abundance than the residential area samples. The WWTP demonstrated removal efficiencies of 50.8 % tetracyclines, 66.8 % sulfonamides, 0.5 logs to 2.5 logs tet genes, and less than 1 log of sul and intI1 genes, as well as 0.5 log to 1 log removal for target bacteria. Except for the total tetracycline concentration and the proportion of tetracycline-resistant bacteria (R 2 = 0.330, P < 0.05), there was no significant correlation between antibiotics and the corresponding resistant bacteria (P > 0.05). In contrast, various relationships were identified between antibiotics and antibiotic resistance genes (P < 0.05). Tet (A) and tet (B) displayed noticeable relationships with both tetracycline and combined antibiotic-resistant bacteria (P < 0.01).
Keyword Antibiotic resistance genes
Antibiotic-resistant bacteria
Wastewater treatment plant
Residential areas
Hospitals
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online ahead of print 18 Oct 2014

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Civil Engineering Publications
School of Chemical Engineering Publications
Official 2015 Collection
 
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Citation counts: TR Web of Science Citation Count  Cited 12 times in Thomson Reuters Web of Science Article | Citations
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