Coupling between resting cerebral perfusion and EEG

O'Gorman, R. L., Poil, S-S., Brandeis, D., Klaver, P., Bollmann, S., Ghisleni, C., Luechinger, R., Martin, E., Shankaranarayanan, A., Alsop, D. C. and Michels, L. (2013) Coupling between resting cerebral perfusion and EEG. Brain Topography, 26 3: 442-457. doi:10.1007/s10548-012-0265-7


Author O'Gorman, R. L.
Poil, S-S.
Brandeis, D.
Klaver, P.
Bollmann, S.
Ghisleni, C.
Luechinger, R.
Martin, E.
Shankaranarayanan, A.
Alsop, D. C.
Michels, L.
Title Coupling between resting cerebral perfusion and EEG
Journal name Brain Topography   Check publisher's open access policy
ISSN 0896-0267
1573-6792
Publication date 2013-07-01
Year available 2012
Sub-type Article (original research)
DOI 10.1007/s10548-012-0265-7
Volume 26
Issue 3
Start page 442
End page 457
Total pages 16
Place of publication New York United States
Publisher Springer New York LLC
Language eng
Subject 2728 Clinical Neurology
2702 Anatomy
2808 Neurology
2741 Radiology Nuclear Medicine and imaging
3614 Radiological and Ultrasound Technology
Formatted abstract
While several studies have investigated interactions between the electroencephalography (EEG) and functional magnetic resonance imaging BOLD signal fluctuations, less is known about the associations between EEG oscillations and baseline brain haemodynamics, and few studies have examined the link between EEG power outside the alpha band and baseline perfusion. Here we compare whole-brain arterial spin labelling perfusion MRI and EEG in a group of healthy adults (n = 16, ten females, median age: 27 years, range 21-48) during an eyes closed rest condition. Correlations emerged between perfusion and global average EEG power in low (delta: 2-4 Hz and theta: 4-7 Hz), middle (alpha: 8-13 Hz), and high (beta: 13-30 Hz and gamma: 30-45 Hz) frequency bands in both cortical and sub-cortical regions. The correlations were predominately positive in middle and high-frequency bands, and negative in delta. In addition, central alpha frequency positively correlated with perfusion in a network of brain regions associated with the modulation of attention and preparedness for external input, and central theta frequency correlated negatively with a widespread network of cortical regions. These results indicate that the coupling between average EEG power/frequency and local cerebral blood flow varies in a frequency specific manner. Our results are consistent with longstanding concepts that decreasing EEG frequencies which in general map onto decreasing levels of activation.
Keyword Arterial spin labelling
EEG power
Resting state
Whole-brain perfusion
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Centre for Advanced Imaging Publications
 
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