Perfluorohexane-encapsulated mesoporous silica nanocapsules as enhancement agents for highly efficient high intensity focused ultrasound (HIFU)

Wang, Xia, Chen, Hangrong, Chen, Yu, Ma, Ming, Zhang, Kun, Li, Faqi, Zheng, Yuanyi, Zeng, Deping, Wang, Qi and Shi, Jianlin (2012) Perfluorohexane-encapsulated mesoporous silica nanocapsules as enhancement agents for highly efficient high intensity focused ultrasound (HIFU). Advanced Materials, 24 6: 785-791. doi:10.1002/adma.201104033


Author Wang, Xia
Chen, Hangrong
Chen, Yu
Ma, Ming
Zhang, Kun
Li, Faqi
Zheng, Yuanyi
Zeng, Deping
Wang, Qi
Shi, Jianlin
Title Perfluorohexane-encapsulated mesoporous silica nanocapsules as enhancement agents for highly efficient high intensity focused ultrasound (HIFU)
Journal name Advanced Materials   Check publisher's open access policy
ISSN 0935-9648
1521-4095
Publication date 2012-02-07
Year available 2012
Sub-type Article (original research)
DOI 10.1002/adma.201104033
Open Access Status Not Open Access
Volume 24
Issue 6
Start page 785
End page 791
Total pages 7
Place of publication Weinheim, Germany
Publisher Wiley
Language eng
Abstract An inorganic enhancement agent (EA) for high-intensity focused ultrasound (HIFU) imaging based on mesoporous silica nanocapsules is presented. The pronounced coagulative necrosis effects demonstrate, both in vitro and in vivo, that the EA can be developed as a highly promising theranostic agent for effective HIFU imaging and therapy owing to its high stability, efficient perfluorohexane loading and release, enhanced tumor ablation capability, and easy uptake by target tissues. Copyright
Keyword Nanocapsules
Silica
Imaging techniques
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Chemical Engineering Publications
Non HERDC
 
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