A "neck-formation" strategy for an antiquenching magnetic/upconversion fluorescent bimodal cancer probe

Chen, Feng, Zhang, Shengjian, Bu, Wenbo, Liu, Xiaohang, Chen, Yu, He, Qianjun, Zhu, Min, Zhang, Lingxia, Zhou, Liangping, Peng, Weijun and Shi, Jianlin (2010) A "neck-formation" strategy for an antiquenching magnetic/upconversion fluorescent bimodal cancer probe. Chemistry - A European Journal, 16 37: 11254-11260. doi:10.1002/chem.201000525


Author Chen, Feng
Zhang, Shengjian
Bu, Wenbo
Liu, Xiaohang
Chen, Yu
He, Qianjun
Zhu, Min
Zhang, Lingxia
Zhou, Liangping
Peng, Weijun
Shi, Jianlin
Title A "neck-formation" strategy for an antiquenching magnetic/upconversion fluorescent bimodal cancer probe
Journal name Chemistry - A European Journal   Check publisher's open access policy
ISSN 0947-6539
1521-3765
Publication date 2010-10-04
Sub-type Article (original research)
DOI 10.1002/chem.201000525
Open Access Status Not yet assessed
Volume 16
Issue 37
Start page 11254
End page 11260
Total pages 7
Place of publication Weinheim, Germany
Publisher Wiley - VCH
Language eng
Formatted abstract
Up to the neck! Bio-safe upconversion fluorescent nanocrystals (NaYF4:ErYb) and biocompatible superparamagnetic iron oxide nanocrystals (SPION) were effectively combined by means of a general "neck- formation" strategy forming a size-controlled Cd2+- and Gd3+-free silica-shielded magnetic upconversion fluorescent oligomer (SMUFO) bimodal cancer probe that offers high resistance to photoquenching as well as a synergistic T2-weighted magnetic resonance enhanced effect (see graphic).
Keyword Antitumor agents
Fluorescence
Imaging agents
Magnetic resonance imaging
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Chemical Engineering Publications
 
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