Projections from the lateral vestibular nucleus to the spinal cord in the mouse

Liang, Huazheng, Bacskai, Timea, Watson, Charles and Paxinos, George (2014) Projections from the lateral vestibular nucleus to the spinal cord in the mouse. Brain Structure and Function, 219 3: 805-815. doi:10.1007/s00429-013-0536-4

Author Liang, Huazheng
Bacskai, Timea
Watson, Charles
Paxinos, George
Title Projections from the lateral vestibular nucleus to the spinal cord in the mouse
Journal name Brain Structure and Function   Check publisher's open access policy
ISSN 1863-2661
Publication date 2014-01-01
Year available 2014
Sub-type Article (original research)
DOI 10.1007/s00429-013-0536-4
Open Access Status Not Open Access
Volume 219
Issue 3
Start page 805
End page 815
Total pages 11
Place of publication Heidelberg, Germany
Publisher Springer Verlag
Language eng
Subject 2702 Anatomy
2722 Histology
2800 Neuroscience
Abstract The present study investigated the projections from the lateral vestibular nucleus (LVe) to the spinal cord using retrograde and anterograde tracers. Retrogradely labeled neurons were found after fluoro-gold injections into both the cervical and lumbar cord, with a smaller number of labeled neurons seen after lumbar cord injections. Labeled neurons in the LVe were found in clusters at caudal levels of the nucleus, and a small gap separated these clusters from labeled neurons in the spinal vestibular nucleus (SpVe). In the anterograde study, BDA-labeled fiber tracts were found in both the ventral and ventrolateral funiculi on the ipsilateral side. These fibers terminated in laminae 6-9. Some fibers were continuous with boutons in contact with motor neurons in both the medial and lateral motor neuron columns. In the lumbar and sacral segments, some collaterals from the ipsilateral vestibulospinal tracts were found on the contralateral side, and these fibers mainly terminated in laminae 6-8. The present study reveals for the first time the fiber terminations of the lateral vestibular nucleus in the mouse spinal cord and therefore enhances future functional studies of the vestibulospinal system.
Keyword Hindbrain
Motor neurons
Spinal cord
Vestibular system
Vestibulospinal tract
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
Queensland Brain Institute Publications
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Citation counts: TR Web of Science Citation Count  Cited 9 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 28 Oct 2014, 01:23:00 EST by Sylvie Pichelin on behalf of Queensland Brain Institute