Lymphatic vascular specification and its modulation during embryonic development

Pichol-Thievend, Cathy, Hogan, Benjamin M. and Francois, Mathias (2014) Lymphatic vascular specification and its modulation during embryonic development. Microvascular Research, 96 3-9. doi:10.1016/j.mvr.2014.07.011

Author Pichol-Thievend, Cathy
Hogan, Benjamin M.
Francois, Mathias
Title Lymphatic vascular specification and its modulation during embryonic development
Journal name Microvascular Research   Check publisher's open access policy
ISSN 0026-2862
Publication date 2014-11-01
Sub-type Article (original research)
DOI 10.1016/j.mvr.2014.07.011
Open Access Status Not Open Access
Volume 96
Start page 3
End page 9
Total pages 7
Place of publication Maryland Heights, MO, United States
Publisher Academic Press
Abstract Despite its essential roles in development and disease, the lymphatic vascular system has been less studied than the blood vascular network. In recent years, significant advances have been made in understanding the mechanisms that regulate lymphatic vessel formation, both during development and in pathological conditions. Remarkably, lymphatic endothelial cells are specified as a subpopulation of pre-existing venous endothelial cells. Here, we summarize the current knowledge of the transcription factor pathways responsible for lymphatic specification and we also focus on the factors that promote or restrict this event.
Keyword Lymphatic endothelial cell
Signalling pathways
Transcription factors
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
Institute for Molecular Bioscience - Publications
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Created: Tue, 21 Oct 2014, 10:45:35 EST by System User on behalf of Institute for Molecular Bioscience