A genome-wide association study for morphometric traits in quarter horse

Meira, Camila Tangari, Farah, Michel Marques, Fortes, Marina R. S., Moore, Stephen S., Pereira, Guilherme L., Silva, Josineudson Augusto V., da Mota, Marcilio Dias S. and Curi, Rogerio Abdallah (2014) A genome-wide association study for morphometric traits in quarter horse. Journal of Equine Veterinary Science, 34 8: 1028-1031. doi:10.1016/j.jevs.2014.05.011

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Author Meira, Camila Tangari
Farah, Michel Marques
Fortes, Marina R. S.
Moore, Stephen S.
Pereira, Guilherme L.
Silva, Josineudson Augusto V.
da Mota, Marcilio Dias S.
Curi, Rogerio Abdallah
Title A genome-wide association study for morphometric traits in quarter horse
Journal name Journal of Equine Veterinary Science   Check publisher's open access policy
ISSN 0737-0806
1542-7412
Publication date 2014-08-01
Year available 2014
Sub-type Article (original research)
DOI 10.1016/j.jevs.2014.05.011
Volume 34
Issue 8
Start page 1028
End page 1031
Total pages 4
Place of publication Maryland Heights, MO, United States
Publisher W.B. Saunders
Language eng
Formatted abstract
A genome-wide association study for morphometric traits was conducted in 184 Quarter Horses, 120 from a racing population, and 64 from a cutting population, which were genotyped using the Illumina EquineSNP50 chip. Association analysis was performed with 42,058 single-nucleotide polymorphisms (SNPs) (after quality control) using Qxpak5 software. The following traits were measured: weight (W), rump length (RL), and body length (BL). These morphometric traits are important for the best performance in race and cutting events. For weight, three SNPs associated (P < .0001) were found on chromosomes (Equus caballus autosomes [ECA]) 2 and 3. For rump length, eight SNPs associated (P < .0001) were found on ECA 2, 3, 6, 7, 9, 21, and 26. On ECA 3 and ECA 8, two SNPs were associated (P < .0001) with body length. So, a total of 13 important chromosomal regions were identified with Q values of 0.53 (SNPs for W), 0.40 (SNPs for RL), and 0.99 (SNPs for BL). Positional and functional candidate genes emerging from this study were WWOX and AAVPR1A. Further studies are required to confirm these associations in other populations.
Keyword Equus caballus
Genetics
Quantitative trait
Single-nucleotide polymorphism
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Alliance for Agriculture and Food Innovation
Official 2015 Collection
 
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