A combination of plant-derived odors reduces corticosterone and oxidative indicators of stress

Spiers, Jereme G., Chen, Hsiao-Jou Cortina, Sernia, Conrad and Lavidis, Nickolas A. (2014) A combination of plant-derived odors reduces corticosterone and oxidative indicators of stress. Chemical Senses, 39 7: 563-569. doi:10.1093/chemse/bju026

Author Spiers, Jereme G.
Chen, Hsiao-Jou Cortina
Sernia, Conrad
Lavidis, Nickolas A.
Title A combination of plant-derived odors reduces corticosterone and oxidative indicators of stress
Journal name Chemical Senses   Check publisher's open access policy
ISSN 1464-3553
Publication date 2014-09-01
Year available 2014
Sub-type Article (original research)
DOI 10.1093/chemse/bju026
Open Access Status Not Open Access
Volume 39
Issue 7
Start page 563
End page 569
Total pages 7
Place of publication Oxford, United Kingdom
Publisher Oxford University Press
Language eng
Formatted abstract
In this study, we measured typical stress markers in addition to oxidative status and reduced glutathione in erythrocytes, and plasma lipid peroxidation of restraint-stressed animals exposed to a combination of plant-derived odors (0.03% Z-3-hexen-1-ol, 0.03% E-2-hexenal, and 0.015% α-pinene in triethyl citrate). Male Wistar rats aged 6–7 weeks postnatal were exposed to vehicle (triethyl citrate, n = 12), plant-derived odors (n = 12), or 1% propionic acid odor (n = 12) under control or stress conditions, and blood samples were collected. Restraint stress increased plasma glucose and plasma corticosterone concentrations by approximately 10% (P < 0.01) and 125% (P < 0.001), respectively, in vehicle-exposed animals. Similar increases were observed in animals exposed to a 1% propionic acid odor, indicating the novelty of odor exposure does not alter stress responsiveness. There was also an increase of approximately 15% in both erythrocytic oxidative status (P < 0.001) and plasma lipid peroxidation (P < 0.05), and a decrease of approximately the same magnitude in reduced glutathione (P < 0.05) in restrained animals with vehicle exposure. There were no differences observed between control and stress treatment with plant-derived odor exposure in any of the measured parameters. It was concluded that exposure to plant-derived odors reduce corticosterone, glucose, and redox responses elicited by psychological stress.
Keyword Acute restraint stress
Lipid peroxidation
Oxidative stress
Reactive oxygen species
Redox status
Reduced glutathione
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Biomedical Sciences Publications
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