Surface-enhanced Raman spectroscopy at single-molecule scale and its implications in biology

Wang, Yuling and Irudayaraj, Joseph. (2013) Surface-enhanced Raman spectroscopy at single-molecule scale and its implications in biology. Philosophical Transactions of the Royal Society B: Biological Sciences, 368 1611: . doi:10.1098/rstb.2012.0026


Author Wang, Yuling
Irudayaraj, Joseph.
Title Surface-enhanced Raman spectroscopy at single-molecule scale and its implications in biology
Journal name Philosophical Transactions of the Royal Society B: Biological Sciences   Check publisher's open access policy
ISSN 0962-8436
1471-2970
Publication date 2013-02-05
Year available 2012
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1098/rstb.2012.0026
Open Access Status DOI
Volume 368
Issue 1611
Total pages 11
Place of publication London, United Kingdom
Publisher The Royal Society Publishing
Language eng
Subject 1100 Agricultural and Biological Sciences
1300 Biochemistry, Genetics and Molecular Biology
Abstract Single-molecule (SM) spectroscopy has been an exciting area of research offering significant promise and hope in the field of sensor development to detect targets at ultra-low levels down to SM resolution. To the experts and developers in the field of surface-enhanced Raman spectroscopy (SERS), this has often been a challenge and a significant opportunity for exploration. Needless to say, the opportunities and excitement of this multidisciplinary area impacts span the fields of physics, chemistry and engineering, along with a significant thrust in applications constituting areas in medicine, biology, environment and agriculture among others. In this review, we will attempt to provide a quick snapshot of the basics of SM-SERS, nanostructures and devices that can enable SM Raman measurement. We will conclude with a discussion on SERS implications in biomedical sciences.
Keyword Biological sciences
Hot spot
Nanotechnology
Single molecule
Surface-enhanced Raman spectroscopy
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
 
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