A new class of animal collagen masquerading as an insect silk

Sutherland, Tara D., Peng, Yong Y., Trueman, Holly E., Weisman, Sarah, Okada, Shoko, Walker, Andrew A., Sriskantha, Alagacone, White, Jacinta F., Huson, Mickey G., Werkmeister, Jerome A., Glattauer, Veronica, Stoichevska, Violet, Mudie, Stephen T., Haritos, Victoria S. and Ramshaw, John A. M. (2013) A new class of animal collagen masquerading as an insect silk. Scientific Reports, 3 . doi:10.1038/srep02864


Author Sutherland, Tara D.
Peng, Yong Y.
Trueman, Holly E.
Weisman, Sarah
Okada, Shoko
Walker, Andrew A.
Sriskantha, Alagacone
White, Jacinta F.
Huson, Mickey G.
Werkmeister, Jerome A.
Glattauer, Veronica
Stoichevska, Violet
Mudie, Stephen T.
Haritos, Victoria S.
Ramshaw, John A. M.
Title A new class of animal collagen masquerading as an insect silk
Journal name Scientific Reports   Check publisher's open access policy
ISSN 2045-2322
Publication date 2013-01-01
Year available 2013
Sub-type Article (original research)
DOI 10.1038/srep02864
Open Access Status DOI
Volume 3
Total pages 6
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Language eng
Subject 1000 General
Abstract Collagen is ubiquitous throughout the animal kingdom, where it comprises some 28 diverse molecules that form the extracellular matrix within organisms. In the 1960s, an extracorporeal animal collagen that forms the cocoon of a small group of hymenopteran insects was postulated. Here we categorically demonstrate that the larvae of a sawfly species produce silk from three small collagen proteins. The native proteins do not contain hydroxyproline, a post translational modification normally considered characteristic of animal collagens. The function of the proteins as silks explains their unusual collagen features. Recombinant proteins could be produced in standard bacterial expression systems and assembled into stable collagen molecules, opening the door to manufacture a new class of artificial collagen materials.
Keyword Multidisciplinary Sciences
Science & Technology - Other Topics
MULTIDISCIPLINARY SCIENCES
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
Institute for Molecular Bioscience - Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 8 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 10 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Thu, 07 Aug 2014, 00:47:15 EST by System User on behalf of Institute for Molecular Bioscience