High aspect ratio elongated microparticles for enhanced topical drug delivery in human volunteers

Raphael, Anthony P., Primiero, Clare A., Lin, Lynlee L., Smith, Ross Flewell, Dyer, Philip, Soyer, H. Peter and Prow, Tarl W. (2014) High aspect ratio elongated microparticles for enhanced topical drug delivery in human volunteers. Advanced Healthcare Materials, 3 6: 860-866. doi:10.1002/adhm.201300517


Author Raphael, Anthony P.
Primiero, Clare A.
Lin, Lynlee L.
Smith, Ross Flewell
Dyer, Philip
Soyer, H. Peter
Prow, Tarl W.
Title High aspect ratio elongated microparticles for enhanced topical drug delivery in human volunteers
Journal name Advanced Healthcare Materials   Check publisher's open access policy
ISSN 2192-2659
2192-2640
Publication date 2014-06-01
Year available 2014
Sub-type Article (original research)
DOI 10.1002/adhm.201300517
Volume 3
Issue 6
Start page 860
End page 866
Total pages 7
Place of publication Weinheim, Germany
Publisher Wiley
Collection year 2015
Language eng
Abstract Delivery of therapeutics into skin is hindered by the epidermal barriers. To overcome these barriers for the treatment of skin diseases, a cutaneous delivery method capable of field treatment using silica-elongated microparticles is developed. The microparticles are massaged into the skin using a 3D-printed microtextured applicator resulting in significant field-directed drug delivery enhancement.
Keyword Drug delivery
Microneedles
Microparticles
Silica
Skin
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Medicine Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 24 Jun 2014, 13:05:09 EST by System User on behalf of Medicine - Princess Alexandra Hospital