The contribution of spontaneous mutations to thermal sensitivity curve variation in drosophila serrata

Latimer, Camille A. L., McGuigan, Katrina, Wilson, Robbie S., Blows, Mark W. and Chenoweth, Stephen F. (2014) The contribution of spontaneous mutations to thermal sensitivity curve variation in drosophila serrata. Evolution, 68 6: 1824-1837. doi:10.1111/evo.12392


Author Latimer, Camille A. L.
McGuigan, Katrina
Wilson, Robbie S.
Blows, Mark W.
Chenoweth, Stephen F.
Title The contribution of spontaneous mutations to thermal sensitivity curve variation in drosophila serrata
Journal name Evolution   Check publisher's open access policy
ISSN 0014-3820
1558-5646
Publication date 2014-01-01
Year available 2014
Sub-type Article (original research)
DOI 10.1111/evo.12392
Open Access Status Not yet assessed
Volume 68
Issue 6
Start page 1824
End page 1837
Total pages 14
Place of publication Oxford, United Kingdom
Publisher Wiley-Blackwell Publishing Ltd.
Language eng
Subject 1100 Agricultural and Biological Sciences
1105 Dentistry
1311 Genetics
Abstract Many traits studied in ecology and evolutionary biology change their expression in response to a continuously varying environmental factor. One well-studied example are thermal performance curves (TPCs); continuous reaction norms that describe the relationship between organismal performance and temperature and are useful for understanding the trade-offs involved in thermal adaptation. We characterized curves describing the thermal sensitivity of voluntary locomotor activity in a set of 66 spontaneous mutation accumulation lines in the fly Drosophila serrata. Factor-analytic modeling of the mutational variance-covariance matrix, M, revealed support for three axes of mutational variation in males and two in females. These independent axes of mutational variance corresponded well to the major axes of TPC variation required for different types of thermal adaptation; "faster-slower" representing changes in performance largely independent of temperature, and the "hotter-colder" and "generalist-specialist" axes, representing trade-offs. In contrast to its near-absence from standing variance in this species, a "faster-slower" axis, accounted for most mutational variance (75% in males and 66% in females) suggesting selection may easily fix or remove these types of mutations in outbred populations. Axes resembling the "hotter-colder" and "generalist-specialist" modes of variation contributed less mutational variance but nonetheless point to an appreciable input of new mutations that may contribute to thermal adaptation.
Keyword Function valued traits
Genetic principal components
Locomotor activity
Mutational bias
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Biological Sciences Publications
 
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