A comprehensive nationwide study of the incidence rate and lifetime risk for treated mental disorders

Pedersen, Carsten Bøcker, Mors, Ole, Bertelsen, Aksel, LindumWaltoft, Berit Lindum, Agerbo, Esben, McGrath, John J., Mortensen, Preben Bo and Eaton, William W. (2014) A comprehensive nationwide study of the incidence rate and lifetime risk for treated mental disorders. JAMA Psychiatry, 71 5: 573-581. doi:10.1001/jamapsychiatry.2014.16

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Author Pedersen, Carsten Bøcker
Mors, Ole
Bertelsen, Aksel
LindumWaltoft, Berit Lindum
Agerbo, Esben
McGrath, John J.
Mortensen, Preben Bo
Eaton, William W.
Title A comprehensive nationwide study of the incidence rate and lifetime risk for treated mental disorders
Journal name JAMA Psychiatry   Check publisher's open access policy
ISSN 2168-622X
2168-6238
Publication date 2014-01-01
Sub-type Article (original research)
DOI 10.1001/jamapsychiatry.2014.16
Open Access Status File (Publisher version)
Volume 71
Issue 5
Start page 573
End page 581
Total pages 9
Place of publication Chicago, IL, United States
Publisher American Medical Association
Language eng
Abstract Understanding the epidemiologic profile of the life course of mental disorders is fundamental for research and planning for health care. Although previous studies have used population surveys, informative and complementary estimates can be derived from population-based registers. OBJECTIVE To derive comprehensive and precise estimates of the incidence rate of and lifetime risk for any mental disorder and a range of specific mental disorders. DESIGN, SETTING, AND PARTICIPANTS We conducted a follow-up study of all Danish residents (5.6 million persons), to whom all treatment is provided by the government health care system without charge to the patient, from January 1, 2000, through December 31, 2012 (total follow-up, 59.5 million person-years). During the study period, 320 543 persons received first lifetime treatment in a psychiatric setting for any mental disorder; 489 006 persons were censored owing to death; and 69 987 persons were censored owing to emigration. Specific categories of mental disorders investigated included organic mental disorders, substance abuse disorders, schizophrenia, mood disorders, anxiety, eating disorders, personality disorders, mental retardation, pervasive developmental disorders, and behavioral and emotional disorders. EXPOSURES Age and sex. MAIN OUTCOMES AND MEASURES Sex- and age-specific incidence rates and cumulative incidences and sex-specific lifetime risks. RESULTS During the course of life, 37.66%of females (95%CI, 37.52%-37.80%) and 32.05% of males (31.91%-32.19%) received their first treatment in a psychiatric setting for any mental disorder. The occurrence of mental disorders varied markedly between diagnostic categories and by sex and age. The sex- and age-specific incidence rates for many mental disorders had a single peak incidence rate during the second and third decades of life. Some disorders had a second peak in the sex- and age-specific incidence rate later in life. CONCLUSIONS AND RELEVANCE This nationwide study provides a first comprehensive assessment of the lifetime risks for treated mental disorders. Approximately one-third of the Danish population received treatment for mental disorders. The distinct signatures of the different mental disorders with respect to sex and age have important implications for service planning and etiologic research.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
Official 2015 Collection
 
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