Benign dermoscopic features in melanoma

Di Stefani, A., Massone, C., Soyer, H. P., Zalaudek, I., Argenziano, G., Arzberger, E., Lozzi, G.P., Chimenti, S. and Hofmann-Wellenhof, R. (2014) Benign dermoscopic features in melanoma. Journal of the European Academy of Dermatology and Venereology, 28 6: 799-804. doi:10.1111/jdv.12192

Author Di Stefani, A.
Massone, C.
Soyer, H. P.
Zalaudek, I.
Argenziano, G.
Arzberger, E.
Lozzi, G.P.
Chimenti, S.
Hofmann-Wellenhof, R.
Title Benign dermoscopic features in melanoma
Journal name Journal of the European Academy of Dermatology and Venereology   Check publisher's open access policy
ISSN 1468-3083
Publication date 2014-01-01
Year available 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1111/jdv.12192
Open Access Status
Volume 28
Issue 6
Start page 799
End page 804
Total pages 6
Place of publication Chichester, West Sussex, United Kingdom
Publisher Blackwell Publishing Ltd
Language eng
Subject 2708 Dermatology
2725 Infectious Diseases
Abstract Background Various dermoscopic features are usually associated with benign melanocytic lesions. Our objective was to determine frequency and extension of benign dermoscopic features (BDF) in melanoma. Methods Retrospective review of dermoscopic images of a consecutive series of 516 histopathologically proven melanomas collected in 6 years in Graz. Correlation of BDF with mean Breslow thickness, with presence/absence of associated benign nevus component and with the pre-operative clinico-dermoscopic diagnosis, as reported on the original histopathologic reports. Results In addition to melanoma specific criteria, 42% of melanomas showed BDF. In 12.3% cases, the benign features occupied more than the half of the lesion. The BDF typical pigment network, homogeneous pattern and regular globules/cobblestone pattern had the highest frequency. BDF were associated with relatively thinner melanomas (mean Breslow thickness of 0.51 mm). The presence of BDF was observed in 67.1% of histopathologically documented nevus-associated melanoma and in 35.7% of melanoma de novo. A pre-operative clinico-dermoscopic diagnosis of melanoma was achieved in only 54.1% of cases displaying BDF. Conclusion A significant proportion of melanomas may exhibit BDF. Clinicians should be aware of the presence of BDF in melanoma as possible diagnostic pitfall.
Keyword Dermatology
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2015 Collection
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