Whole-genome association study of fatty acid composition in a diverse range of beef cattle breeds

Kelly, M. J., Tume, R. K., Fortes, M. and Thompson, J. M. (2014) Whole-genome association study of fatty acid composition in a diverse range of beef cattle breeds. Journal of Animal Science, 92 5: 1895-1901. doi:10.2527/jas2013-6901


Author Kelly, M. J.
Tume, R. K.
Fortes, M.
Thompson, J. M.
Title Whole-genome association study of fatty acid composition in a diverse range of beef cattle breeds
Journal name Journal of Animal Science   Check publisher's open access policy
ISSN 1525-3163
0021-8812
Publication date 2014-05-01
Year available 2014
Sub-type Article (original research)
DOI 10.2527/jas2013-6901
Volume 92
Issue 5
Start page 1895
End page 1901
Total pages 7
Place of publication Champaign, IL, United States
Publisher American Society of Animal Science
Language eng
Formatted abstract
Fatty acid composition of adipose tissue associated with meat is an important factor for the beef industry because of its implications for human health, processing, meat quality, and palatability. Individual fatty acid composition is a trait under genetic control, so improvement via selective breeding of cattle is possible. The objective of this study was to investigate the genetic architecture of fatty acid composition and identify genes associated with this trait in 3 breed types: Bos indicus (Brahman), Bos taurus (4 breeds), and tropically adapted composites (2 breeds). Using high-density data, regions on chromosomes 1, 9, 14, 16, 19, 23, 26, 29, and X were associated with fat composition and quantity traits. Known candidate genes, such as fatty acid synthase (FASN; chromosome 19) and stearoyl-CoA desaturase (SCD; chromosome 26), were confirmed in our results. Other candidate genes and regions represent novel association results, requiring further validation.
Keyword Fatty acid composition
Genome-wide association study
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Alliance for Agriculture and Food Innovation
Official 2015 Collection
 
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