Adverse lipid profile is not associated with relapse risk in MS: results from an observational cohort study

Tettey, Prudence, Simpson Jr., Steve, Taylor, Bruce, Blizzard, Leigh, Ponsonby, Anne-Louise, Dwyer, Terence, Kostner, Karam and Van Der Mei, Ingrid (2014) Adverse lipid profile is not associated with relapse risk in MS: results from an observational cohort study. Journal of the Neurological Sciences, 340 1-2: 230-232. doi:10.1016/j.jns.2014.02.038


Author Tettey, Prudence
Simpson Jr., Steve
Taylor, Bruce
Blizzard, Leigh
Ponsonby, Anne-Louise
Dwyer, Terence
Kostner, Karam
Van Der Mei, Ingrid
Title Adverse lipid profile is not associated with relapse risk in MS: results from an observational cohort study
Journal name Journal of the Neurological Sciences   Check publisher's open access policy
ISSN 1878-5883
0022-510X
Publication date 2014-05-15
Year available 2014
Sub-type Article (original research)
DOI 10.1016/j.jns.2014.02.038
Volume 340
Issue 1-2
Start page 230
End page 232
Total pages 3
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Language eng
Formatted abstract
Background
There is increasing evidence that serum lipids and apolipoproteins may be associated with multiple sclerosis (MS) clinical course.

Objective
To investigate the associations between serum lipids, apolipoproteins, body mass index and relapse in MS.

Methods
A prospective cohort of 141 participants with relapsing–remitting MS was followed from 2002 to 2005. Serum lipid and apolipoprotein levels were measured biannually, and body mass index at baseline. The association with hazard of relapse was assessed using survival analysis.

Results
Neither body mass index nor any of the lipid-related measures were associated with the hazard of relapse.

Conclusion
Serum lipid profile and body mass index are not associated with the hazard of relapse in MS.
Keyword Lipid
Cholesterol
Apolipoprotein
Relapse
Multiple sclerosis
Profile
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Medicine Publications
 
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