Obesity paradox, cachexia, frailty, and heart failure

Lavie, Carl J., De Schutter, Alban, Alpert, Martin A., Mehra, Mandeep R., Milani, Richard V. and Ventura, Hector O. (2014) Obesity paradox, cachexia, frailty, and heart failure. Heart Failure Clinics, 10 2: 319-326. doi:10.1016/j.hfc.2013.12.002

Author Lavie, Carl J.
De Schutter, Alban
Alpert, Martin A.
Mehra, Mandeep R.
Milani, Richard V.
Ventura, Hector O.
Title Obesity paradox, cachexia, frailty, and heart failure
Journal name Heart Failure Clinics   Check publisher's open access policy
ISSN 1551-7136
Publication date 2014-01-01
Year available 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.hfc.2013.12.002
Open Access Status Not yet assessed
Volume 10
Issue 2
Start page 319
End page 326
Total pages 8
Place of publication Maryland Heights, MO United States
Publisher W.B. Saunders Co.
Language eng
Abstract Overweight and obesity adversely affect cardiovascular (CV) risk factors and CV structure and function, and lead to a marked increase in the risk of developing heart failure (HF). Despite this, an obesity paradox exists, wherein those who are overweight and obese with HF have a better prognosis than their leaner counterparts, and the underweight, frail, and cachectic have a particularly poor prognosis. In light of this, the potential benefits of exercise training and efforts to improve cardiorespiratory fitness, as well as the potential for weight reduction, especially in severely obese patients with HF, are discussed.
Keyword Cachexia
Heart failure
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2015 Collection
School of Medicine Publications
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